Detalhe da pesquisa
1.
Puerarin ameliorated pressure overload-induced cardiac hypertrophy in ovariectomized rats through activation of the PPARα/PGC-1 pathway.
Acta Pharmacol Sin
; 42(1): 55-67, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504066
2.
Contributions of Nrf2 to Puerarin Prevention of Cardiac Hypertrophy and its Metabolic Enzymes Expression in Rats.
J Pharmacol Exp Ther
; 366(3): 458-469, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945930
3.
Novel naftopidil derivatives containing methyl phenylacetate and their blocking effects on α1D/1A-adrenoreceptor subtypes.
Bioorg Med Chem Lett
; 28(4): 547-551, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29422390
4.
[Pharmacokinetic Effect of Acteoside in Blood Deficiency Rats].
Zhong Yao Cai
; 39(2): 395-7, 2016 Feb.
Artigo
em Zh
| MEDLINE | ID: mdl-30080375
5.
[Pharmacokinetic Study on Brucine in Different Administration Methods of Liposome in Rats].
Zhong Yao Cai
; 38(10): 2125-8, 2015 Oct.
Artigo
em Zh
| MEDLINE | ID: mdl-27254928
6.
Simultaneous stereoselective analysis of naftopidil and O-desmethyl naftopidil enantiomers in rat feces using an online column-switching high-performance liquid chromatography method.
Biomed Chromatogr
; 28(7): 1030-5, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24420149
7.
Azilsartan ameliorates ventricular hypertrophy in rats suffering from pressure overload-induced cardiac hypertrophy by activating the Keap1-Nrf2 signalling pathway.
J Pharm Pharmacol
; 73(12): 1715-1725, 2021 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343333
8.
Inhibitory effect of α1D/1A antagonist 2-(1H-indol-3-yl)-N-[3-(4-(2-methoxyphenyl) piperazinyl) propyl] acetamide on estrogen/androgen-induced rat benign prostatic hyperplasia model in vivo.
Eur J Pharmacol
; 870: 172817, 2020 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31756334
9.
Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats.
Front Pharmacol
; 9: 540, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29928229
10.
Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro.
Front Pharmacol
; 8: 984, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29375383
11.
Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress.
Naunyn Schmiedebergs Arch Pharmacol
; 390(5): 535-545, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28210753
12.
Pharmaceutical evaluation of naftopidil enantiomers: Rat functional assays in vitro and estrogen/androgen induced rat benign prostatic hyperplasia model in vivo.
Eur J Pharmacol
; 791: 473-481, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27615445
13.
Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration.
Int J Pharm
; 410(1-2): 138-44, 2011 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21392565
14.
Determination of puerarin in rat plasma by rapid resolution liquid chromatography tandem mass spectrometry in positive ionization mode.
J Chromatogr B Analyt Technol Biomed Life Sci
; 879(19): 1497-501, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21511546