1.
Chem Biodivers
; 7(11): 2702-8, 2010 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21072769
RESUMO
Chemical investigation of the AcOEt/MeOH extract of Clavularia viridis collected in Taiwan has afforded four new prostanoids, named claviridins A-D (1-4, resp.). The structures of compounds 1-4 were determined on the basis of 1D- and 2D-NMR techniques, including COSY, HMQC, HMBC, and NOESY experiments. Pharmacological studies revealed that compounds 1-4 exhibited potent cytotoxicity against human cancer cells.