RESUMO
AIM: The aim of this study was to determine whether bone formation around surface-conditioned implants is enhanced compared with non-surface-conditioned sandblasted acid-etched titanium implants. MATERIALS AND METHODS: One hundred and forty-four implants were placed in the mandible of 18 minipigs. Before placement, implants were either surface conditioned in a solution containing hydroxide ions (conSF) or assigned to controls. Animals were euthanized after 2, 4 and 8 weeks of submerged healing, the 8-week group receiving polyfluorochrome labelling at week 2, 4, 6 and 8. One jaw quadrant per animal was selected for histological and histomorphometrical evaluation of mineralized bone-implant contact (mBIC), osteoid-implant contact (OIC) and bone volume (BV) analysis. RESULTS: Polyfluorochrome labelling showed no general differences in bone dynamics. mBIC showed the most pronounced differences after 2 weeks, reaching 65.5% for conSF compared with 48.1% for controls, p=0.270. Differences levelled out after 4 weeks (67.4% control, 65.7% conSF) and 8 weeks (64.0% control, 70.2% conSF). OIC levels were initially comparable, showing a slower decline for conSF after 4 weeks. BV was higher for conSF at all times. No significant differences could be found. CONCLUSION: A tendency towards increased mBIC was shown for surface-conditioned implants after short-term healing.
Assuntos
Materiais Revestidos Biocompatíveis/química , Corrosão Dentária/métodos , Implantes Dentários , Planejamento de Prótese Dentária , Osteogênese/fisiologia , Condicionamento Ácido do Dente/métodos , Animais , Antraquinonas , Matriz Óssea/patologia , Calcificação Fisiológica/fisiologia , Implantação Dentária Endóssea , Materiais Dentários/química , Doxiciclina , Feminino , Fluoresceínas , Corantes Fluorescentes , Hidróxidos/química , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Mandíbula/cirurgia , Modelos Animais , Osseointegração/fisiologia , Fenóis , Radiografia , Sulfóxidos , Propriedades de Superfície , Suínos , Porco Miniatura , Fatores de Tempo , Titânio/química , XilenosRESUMO
Two groups of titanium dental implants, identical in geometry but different in the treatment of their surfaces, were tested in an in vivo minipig model of the mandible. The surfaces that were tested were, first, sandblasted and acid-etched; and secondly, sandblasted, acid-etched, and conditioned. The removal torque was assessed at 2, 4, and 8 weeks after implantation (n=6 animals in each healing period). The interfacial stiffness was also evaluated. All dental implants were well-integrated at the time of death. Removal torque values increased significantly over the course of 8 weeks. Removal torque and interfacial stiffness were increased for conditioned surfaces after 2 weeks, but there were no significant differences between the two surfaces. The sandblasted and acid-etched implants are the standard, and conditioning of the surface showed a tendency to increase early peri-implant formation of bone.