Detalhe da pesquisa
1.
Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer.
J Biol Chem
; 295(8): 2348-2358, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959629
2.
Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer.
Lab Invest
; 101(2): 177-192, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33009500
3.
Transgenic Expression of PRSS1R122H Sensitizes Mice to Pancreatitis.
Gastroenterology
; 158(4): 1072-1082.e7, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419436
4.
Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
Gastroenterology
; 157(5): 1413-1428.e11, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31352001
5.
Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis.
Am J Physiol Gastrointest Liver Physiol
; 316(1): G179-G186, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431318
6.
Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.
Gastroenterology
; 154(5): 1524-1537.e6, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29274868
7.
Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS.
Cell Commun Signal
; 17(1): 19, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819189
8.
RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer.
Biochem Biophys Res Commun
; 493(1): 592-597, 2017 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28867179
9.
Correction to: Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer.
Lab Invest
; 101(9): 1304, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079044
10.
TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.
Cell Physiol Biochem
; 39(2): 740-50, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27459514
11.
Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics.
Am J Physiol Gastrointest Liver Physiol
; 309(5): G283-91, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26159697
12.
Study human pancreatic cancer in mice: how close are they?
Biochim Biophys Acta
; 1835(1): 110-8, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23147198
13.
Roles for KRAS in pancreatic tumor development and progression.
Gastroenterology
; 144(6): 1220-9, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622131
14.
Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice.
Gastroenterology
; 144(1): 202-10, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23041324
15.
A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.
Gastroenterology
; 145(6): 1449-58, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23958541
16.
Early elevations of RAS protein level and activity are critical for the development of PDAC in the context of inflammation.
Cancer Lett
; 586: 216694, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38307409
17.
Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in ß cells and mice.
Gastroenterology
; 143(6): 1510-1517.e1, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22960655
18.
Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.
Gut
; 61(9): 1315-22, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22068166
19.
Acinar Ductal Metaplasia: Yap Fills a Gap.
Gastroenterology
; 151(3): 393-5, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27456389
20.
Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.
Gastroenterology
; 141(4): 1451-62, 1462.e1-6, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21763240