Mapping the Minnesota Living with Heart Failure Questionnaire (MLHFQ) to SF-6Dv2 in Chinese patients with heart failure.

PURPOSE: Mapping the Minnesota Living with Heart Failure Questionnaire (MLHFQ) to SF-6Dv2 in Chinese patients with chronic heart failure, and to obtain the health utility value for health economic assessment. METHODS: Four statistical algorithms, including ordinary least square method (OLS), Tobit model, robust MM estimator (MM) and censored least absolute deviations (CLAD), were used to establish the alternative model. Models were validated by using a tenfold cross-validation technique. The mean absolute error (MAE) and root mean square error (RMSE) were used to evaluate the prediction performance of the model. The Spearman correlation coefficient and Intraclass Correlation Coefficients (ICC) were used to examine the relationship between the predicted and observed SF-6Dv2 values. RESULTS: A total of 195 patients with chronic heart failure were recruited from 3 general hospitals in Beijing. The MLHFQ summary score and domain scores of the study sample were negatively correlated with SF-6Dv2 health utility value. The OLS regression model established based on the MLHFQ domain scores was the optimal fitting model and the predicted value was highly positively correlated with the observed value. CONCLUSION: The MLHFQ can be mapped to SF-6Dv2 by OLS, which can be used for health economic assessment of cardiovascular diseases such as chronic heart failure.

Association of self-leadership and epidemic risk perception on quality of life in post-pandemic mainland of China: a cross-sectional study.

Background: Self-leadership has proven to adjust individual psychological states and promote active behaviors to mitigate stress perception and negative lifestyle. This study aims to investigate the relationship between self-leadership, epidemic risk perception, and quality of life among the general public in post-pandemic mainland of China. Methods: Two online self-reported questionnaire surveys were carried out with 3,098 and 469 people in the Chinese mainland in February 2021 and December 2022, respectively. The univariate analysis, structural equation modeling, and fuzzy-set qualitative comparative analysis were used to analyze the data which was collected by Revised Self-Leadership Questionnaire, Perceived Risk of COVID-19 Pandemic Scale and World Health Organization Quality of Life Brief Scale. Results: The Self-leadership was directly, moderately, and positively correlated with quality of life (Standardized path coefficients: 0.383 and 0.491, respectively; p < 0.05), and epidemic risk perception was negatively correlated with quality of life (Standardized path: 0.068 and 0.120, respectively; p < 0.05). The structural equation model for self-leadership, epidemic risk perception, and quality of life had a good fit (CFI = 0.957, 0.939 > 0.9; RSMEA = 0.058, 0.064 < 0.08, respectively) and was consistent across genders, educational levels, and types of occupations (Delata-CFI < 0.01). The core condition for achieving a high quality of life lies in maintaining a low level of self-punishment and a high level of self-cueing or a high level of self-punishment and a low level of self-cueing. Conclusion: In the post-epidemic era, the public can adjust their attitude toward stress by enhancing their self-leadership skills. Among various self-leadership skills, self-punishment or self-cueing may have the most significant impact on the quality of life.

Study on Gas Adsorption-Desorption and Diffusion Behaviour in Coal Pores Modified by Nano Fracturing Fluid.

Nanoparticles are added to clean fracturing fluids to formulate nanoparticle-modified clean fracturing fluids, compared with ordinary clean fracturing fluid, it has the advantages of good temperature resistance, low loss of filtration, and so forth, and has good application prospects in coal-bed methane. However, the current research on nanoparticle-modified clean fracturing fluids is mostly focused on the study of their rheological properties. The mechanism of nano-fracking fluid influence on methane adsorption-desorption characteristics is not clear. Therefore, this study chooses Jiulishan anthracite coal (high-rank coal), Pingdingshan coal (medium-rank coal), and Geng village mine long bituminous coal (low-rank coal) of the three rank coal samples. Using indoor experiments and molecular simulation methods, a study on the influence of methane adsorption and desorption capacity and diffusion ability of coal samples provides a modified fracturing fluid formulation of 0.8% CATB + 0.2% NaSal + 1% KCl + SiO2. The experimental results show that nanofracturing fluid-treated coal samples compared to clean fracturing fluid treated coal samples, both methane adsorption and desorption capacities, were increased to some extent. Construction of methane adsorption systems with different apertures and calculation of isosteric heat of adsorption, indicating that the interaction force between methane and coal molecules is smaller after nanofracturing fluid treatment, which facilitated methane desorption. A simulation study of methane diffusion in coal samples treated with two systems of fracturing fluids at different aperture was carried out using molecular dynamics methods, indicating that nanoparticle-modified clean fracturing fluids can reduce the damage of clean fracturing fluids to the desorption-diffusion ability of coal reservoirs. Comparison of 6 MPa as the most suitable pressure for nanofracturing fluids to function provides a basis for the future development of nanofracturing fluids and their popularization.

Minimum clinically important differences in the Minnesota Living with Heart Failure questionnaire: from a study of heart failure patients treated with integrated Chinese and Western medicine.

Objective: The purpose of this study was to estimate the minimum clinically important differences (MCIDs) in the Minnesota Living with Heart Failure questionnaire (MLHFQ), which targeted patients with heart failure treated with integrated Chinese and Western medicine, as a means of helping doctors and patients judge the effectiveness of intervention. Methods: A total of 194 patients with chronic heart failure were recruited from three general hospitals in Beijing. Anchor-based and distribution-based approaches were used to estimate MCID. The anchor was SF-36 item 2 (HT, Health Transition), and the calculation methods included the mean change method, receiver operating characteristic (ROC) curve analysis, and linear regression model. For the distribution-based approaches, 0.2, 0.5, and 0.8 standardized response mean (SRM) values and standard error of measurement (SEM) value of 1 were used. Results: The correlation coefficients of the MLHFQ scale information and HT were 0.346-0.583. Different MCIDs were obtained by the mean change method, ROC curve, and linear regression model. The minimum MCID in the physical domain, emotional domain, and total scores were 3.6, 2.0, and 7.4, respectively; the maximum estimates were 9.5, 2.5, and 13.0, respectively; and the average estimates were 5.7, 2.2, and 10.0, respectively. The average estimates were close to the result of the 0.5 SRM or 1 SEM. Conclusion: We established MCIDs in the MLHFQ using anchor-based and distribution-based approaches. It was recommended to round the average estimates of anchor-based approaches up to the nearest whole number for the MCIDs of the MLHFQ physical domain, emotional domain, and total scores. The results were 6.0, 2.0, and 10.0, respectively.