Pesquisa | BVS Violência e Saúde

1.

Transposon-triggered innate immune response confers cancer resistance to the blind mole rat.

Zhao, Yang; Oreskovic, Ena; Zhang, Quanwei; Lu, Quan; Gilman, Abbey; Lin, Yifei S; He, Junyue; Zheng, Zhizhong; Lu, J Yuyang; Lee, Jina; Ke, Zhonghe; Ablaeva, Julia; Sweet, Matthew J; Horvath, Steve; Zhang, Zhengdong; Nevo, Eviatar; Seluanov, Andrei; Gorbunova, Vera.

Nat Immunol ; 22(10): 1219-1230, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34556881

2.

Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.

Zhang, Zhihui; Tian, Xiao; Lu, J Yuyang; Boit, Kathryn; Ablaeva, Julia; Zakusilo, Frances Tolibzoda; Emmrich, Stephan; Firsanov, Denis; Rydkina, Elena; Biashad, Seyed Ali; Lu, Quan; Tyshkovskiy, Alexander; Gladyshev, Vadim N; Horvath, Steve; Seluanov, Andrei; Gorbunova, Vera.

Nature ; 621(7977): 196-205, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37612507

3.

RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.

Bi, Xianju; Xu, Yanhui; Li, Tong; Li, Xinmin; Li, Wenzhi; Shao, Wen; Wang, Kaili; Zhan, Ge; Wu, Zhongyang; Liu, Wei; Lu, J Yuyang; Wang, Liang; Zhao, Jicheng; Wu, Jiawei; Na, Jie; Li, Guohong; Li, Pilong; Shen, Xiaohua.

Mol Cell ; 75(1): 102-116.e9, 2019 07 11.

Artigo em Inglês | MEDLINE | ID: mdl-31128943

4.

U1 snRNP regulates chromatin retention of noncoding RNAs.

Yin, Yafei; Lu, J Yuyang; Zhang, Xuechun; Shao, Wen; Xu, Yanhui; Li, Pan; Hong, Yantao; Cui, Li; Shan, Ge; Tian, Bin; Zhang, Qiangfeng Cliff; Shen, Xiaohua.

Nature ; 580(7801): 147-150, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-32238924

5.

Phase separation of RNA-binding protein promotes polymerase binding and transcription.

Shao, Wen; Bi, Xianju; Pan, Yixuan; Gao, Boyang; Wu, Jun; Yin, Yafei; Liu, Zhimin; Peng, Mengyuan; Zhang, Wenhao; Jiang, Xu; Ren, Wenlin; Xu, Yanhui; Wu, Zhongyang; Wang, Kaili; Zhan, Ge; Lu, J Yuyang; Han, Xue; Li, Tong; Wang, Jianlong; Li, Guohong; Deng, Haiteng; Li, Bing; Shen, Xiaohua.

Nat Chem Biol ; 18(1): 70-80, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34916619

6.

Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome.

Liu, Lichao; Li, Tong; Song, Guang; He, Qingxia; Yin, Yafei; Lu, J Yuyang; Bi, Xianju; Wang, Kaili; Luo, Sai; Chen, Yu-Sheng; Yang, Ying; Sun, Bao-Fa; Yang, Yun-Gui; Wu, Jiawei; Zhu, Heng; Shen, Xiaohua.

Nucleic Acids Res ; 47(5): 2244-2262, 2019 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-30698743

7.

Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence.

Han, Xue; Xing, Linqing; Hong, Yantao; Zhang, Xuechun; Hao, Bo; Lu, J Yuyang; Huang, Mengyuan; Wang, Zuhui; Ma, Shaoqian; Zhan, Ge; Li, Tong; Hao, Xiaowen; Tao, Yibing; Li, Guanwen; Zhou, Shuqin; Zheng, Zheng; Shao, Wen; Zeng, Yitian; Ma, Dacheng; Zhang, Wenhao; Xie, Zhen; Deng, Haiteng; Yan, Jiangwei; Deng, Wulan; Shen, Xiaohua.

Cell Stem Cell ; 31(5): 694-716.e11, 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38631356

8.

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.

Zhao, Yang; Zheng, Zhizhong; Zhang, Zhihui; Xu, Yandong; Hillpot, Eric; Lin, Yifei S; Zakusilo, Frances T; Lu, J Yuyang; Ablaeva, Julia; Biashad, Seyed Ali; Miller, Richard A; Nevo, Eviatar; Seluanov, Andrei; Gorbunova, Vera.

Nat Commun ; 14(1): 8054, 2023 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-38052795

9.

Evolution of High-Molecular-Mass Hyaluronic Acid is Associated with Subterranean Lifestyle.

Zhao, Yang; Zheng, Zhizhong; Zhang, Zhihui; Hillpot, Eric; Lin, Yifei S; Zakusilo, Frances T; Lu, J Yuyang; Ablaeva, Julia; Miller, Richard A; Nevo, Eviatar; Seluanov, Andrei; Gorbunova, Vera.

bioRxiv ; 2023 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-37215017

10.

Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation.

Lu, J Yuyang; Simon, Matthew; Zhao, Yang; Ablaeva, Julia; Corson, Nancy; Choi, Yongwook; Yamada, KayLene Y H; Schork, Nicholas J; Hood, Wendy R; Hill, Geoffrey E; Miller, Richard A; Seluanov, Andrei; Gorbunova, Vera.

Cell Metab ; 34(6): 836-856.e5, 2022 06 07.

Artigo em Inglês | MEDLINE | ID: mdl-35580607

11.

Long-lived fish in a big pond.

Lu, J Yuyang; Seluanov, Andrei; Gorbunova, Vera.

Science ; 374(6569): 824-825, 2021 Nov 12.

Artigo em Inglês | MEDLINE | ID: mdl-34762450

12.

LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency.

Yan, Pixi; Lu, J Yuyang; Niu, Jing; Gao, Juntao; Zhang, Michael Q; Yin, Yafei; Shen, Xiaohua.

J Mol Cell Biol ; 13(4): 295-313, 2021 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-33049031

13.

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome.

Lu, J Yuyang; Chang, Lei; Li, Tong; Wang, Ting; Yin, Yafei; Zhan, Ge; Han, Xue; Zhang, Ke; Tao, Yibing; Percharde, Michelle; Wang, Liang; Peng, Qi; Yan, Pixi; Zhang, Hui; Bi, Xianju; Shao, Wen; Hong, Yantao; Wu, Zhongyang; Ma, Runze; Wang, Peizhe; Li, Wenzhi; Zhang, Jing; Chang, Zai; Hou, Yingping; Zhu, Bing; Ramalho-Santos, Miguel; Li, Pilong; Xie, Wei; Na, Jie; Sun, Yujie; Shen, Xiaohua.

Cell Res ; 31(6): 613-630, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33514913

14.

DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation.

Zhang, Hui; Wu, Zhongyang; Lu, J Yuyang; Huang, Bo; Zhou, Hongwei; Xie, Wei; Wang, Jianlong; Shen, Xiaohua.

Cell Rep ; 30(1): 81-97.e7, 2020 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-31914400

15.

Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation.

Lu, J Yuyang; Shao, Wen; Chang, Lei; Yin, Yafei; Li, Tong; Zhang, Hui; Hong, Yantao; Percharde, Michelle; Guo, Lerui; Wu, Zhongyang; Liu, Lichao; Liu, Wei; Yan, Pixi; Ramalho-Santos, Miguel; Sun, Yujie; Shen, Xiaohua.

Cell Rep ; 30(10): 3296-3311.e5, 2020 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-32160538

16.

IDH1 fine-tunes cap-dependent translation initiation.

Liu, Lichao; Lu, J Yuyang; Li, Fajin; Xing, Xudong; Li, Tong; Yang, Xuerui; Shen, Xiaohua.

J Mol Cell Biol ; 11(10): 816-828, 2019 10 25.

Artigo em Inglês | MEDLINE | ID: mdl-31408165

17.

Cis- and trans-acting lncRNAs in pluripotency and reprogramming.

Yan, Pixi; Luo, Sai; Lu, J Yuyang; Shen, Xiaohua.

Curr Opin Genet Dev ; 46: 170-178, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-28843809

18.

Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells.

Luo, Sai; Lu, J Yuyang; Liu, Lichao; Yin, Yafei; Chen, Chunyan; Han, Xue; Wu, Bohou; Xu, Ronggang; Liu, Wei; Yan, Pixi; Shao, Wen; Lu, Zhi; Li, Haitao; Na, Jie; Tang, Fuchou; Wang, Jianlong; Zhang, Yong E; Shen, Xiaohua.

Cell Stem Cell ; 18(5): 637-52, 2016 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-26996597

19.

Mouse knockout models reveal largely dispensable but context-dependent functions of lncRNAs during development.

Han, Xue; Luo, Sai; Peng, Guangdun; Lu, J Yuyang; Cui, Guizhong; Liu, Lichao; Yan, Pixi; Yin, Yafei; Liu, Wei; Wang, Ran; Zhang, Jiejie; Ai, Shanshan; Chang, Zai; Na, Jie; He, Aibin; Jing, Naihe; Shen, Xiaohua.

J Mol Cell Biol ; 10(2): 175-178, 2018 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-29420831

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