Pesquisa | BVS Violência e Saúde

1.

Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks.

Jaeger-Ruckstuhl, Carla A; Lo, Yun; Fulton, Elena; Waltner, Olivia G; Shabaneh, Tamer B; Simon, Sylvain; Muthuraman, Pranav V; Correnti, Colin E; Newsom, Oliver J; Engstrom, Ian A; Kanaan, Sami B; Bhise, Shruti S; Peralta, Jobelle M C; Ruff, Raymond; Price, Jason P; Stull, Sylvia M; Stevens, Andrew R; Bugos, Grace; Kluesner, Mitchell G; Voillet, Valentin; Muhunthan, Vishaka; Morrish, Fionnuala; Olson, James M; Gottardo, Raphaël; Sarthy, Jay F; Henikoff, Steven; Sullivan, Lucas B; Furlan, Scott N; Riddell, Stanley R.

Immunity ; 57(2): 287-302.e12, 2024 Feb 13.

Artigo em Inglês | MEDLINE | ID: mdl-38354704

2.

Metabolic Frugality Marks Cancer Cells for Immune Targeting.

Sullivan, Lucas B.

Cell ; 174(6): 1344-1346, 2018 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-30193108

3.

A Broad-Spectrum Inhibitor of CRISPR-Cas9.

Harrington, Lucas B; Doxzen, Kevin W; Ma, Enbo; Liu, Jun-Jie; Knott, Gavin J; Edraki, Alireza; Garcia, Bianca; Amrani, Nadia; Chen, Janice S; Cofsky, Joshua C; Kranzusch, Philip J; Sontheimer, Erik J; Davidson, Alan R; Maxwell, Karen L; Doudna, Jennifer A.

Cell ; 170(6): 1224-1233.e15, 2017 Sep 07.

Artigo em Inglês | MEDLINE | ID: mdl-28844692

4.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Olenchock, Benjamin A; Moslehi, Javid; Baik, Alan H; Davidson, Shawn M; Williams, Jeremy; Gibson, William J; Chakraborty, Abhishek A; Pierce, Kerry A; Miller, Christine M; Hanse, Eric A; Kelekar, Ameeta; Sullivan, Lucas B; Wagers, Amy J; Clish, Clary B; Vander Heiden, Matthew G; Kaelin, William G.

Cell ; 164(5): 884-95, 2016 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-26919427

5.

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

Sullivan, Lucas B; Gui, Dan Y; Hosios, Aaron M; Bush, Lauren N; Freinkman, Elizaveta; Vander Heiden, Matthew G.

Cell ; 162(3): 552-63, 2015 Jul 30.

Artigo em Inglês | MEDLINE | ID: mdl-26232225

6.

Increased demand for NAD⁺ relative to ATP drives aerobic glycolysis.

Luengo, Alba; Li, Zhaoqi; Gui, Dan Y; Sullivan, Lucas B; Zagorulya, Maria; Do, Brian T; Ferreira, Raphael; Naamati, Adi; Ali, Ahmed; Lewis, Caroline A; Thomas, Craig J; Spranger, Stefani; Matheson, Nicholas J; Vander Heiden, Matthew G.

Mol Cell ; 81(4): 691-707.e6, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33382985

7.

A non-canonical tricarboxylic acid cycle underlies cellular identity.

Arnold, Paige K; Jackson, Benjamin T; Paras, Katrina I; Brunner, Julia S; Hart, Madeleine L; Newsom, Oliver J; Alibeckoff, Sydney P; Endress, Jennifer; Drill, Esther; Sullivan, Lucas B; Finley, Lydia W S.

Nature ; 603(7901): 477-481, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35264789

8.

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.

Lanz, Tobias V; Brewer, R Camille; Ho, Peggy P; Moon, Jae-Seung; Jude, Kevin M; Fernandez, Daniel; Fernandes, Ricardo A; Gomez, Alejandro M; Nadj, Gabriel-Stefan; Bartley, Christopher M; Schubert, Ryan D; Hawes, Isobel A; Vazquez, Sara E; Iyer, Manasi; Zuchero, J Bradley; Teegen, Bianca; Dunn, Jeffrey E; Lock, Christopher B; Kipp, Lucas B; Cotham, Victoria C; Ueberheide, Beatrix M; Aftab, Blake T; Anderson, Mark S; DeRisi, Joseph L; Wilson, Michael R; Bashford-Rogers, Rachael J M; Platten, Michael; Garcia, K Christopher; Steinman, Lawrence; Robinson, William H.

Nature ; 603(7900): 321-327, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35073561

9.

A scoutRNA Is Required for Some Type V CRISPR-Cas Systems.

Harrington, Lucas B; Ma, Enbo; Chen, Janice S; Witte, Isaac P; Gertz, Dov; Paez-Espino, David; Al-Shayeb, Basem; Kyrpides, Nikos C; Burstein, David; Banfield, Jillian F; Doudna, Jennifer A.

Mol Cell ; 79(3): 416-424.e5, 2020 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-32645367

10.

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.

Dingler, Felix A; Wang, Meng; Mu, Anfeng; Millington, Christopher L; Oberbeck, Nina; Watcham, Sam; Pontel, Lucas B; Kamimae-Lanning, Ashley N; Langevin, Frederic; Nadler, Camille; Cordell, Rebecca L; Monks, Paul S; Yu, Rui; Wilson, Nicola K; Hira, Asuka; Yoshida, Kenichi; Mori, Minako; Okamoto, Yusuke; Okuno, Yusuke; Muramatsu, Hideki; Shiraishi, Yuichi; Kobayashi, Masayuki; Moriguchi, Toshinori; Osumi, Tomoo; Kato, Motohiro; Miyano, Satoru; Ito, Etsuro; Kojima, Seiji; Yabe, Hiromasa; Yabe, Miharu; Matsuo, Keitaro; Ogawa, Seishi; Göttgens, Berthold; Hodskinson, Michael R G; Takata, Minoru; Patel, Ketan J.

Mol Cell ; 80(6): 996-1012.e9, 2020 12 17.

Artigo em Inglês | MEDLINE | ID: mdl-33147438

11.

A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.

Wright, Addison V; Wang, Joy Y; Burstein, David; Harrington, Lucas B; Paez-Espino, David; Kyrpides, Nikos C; Iavarone, Anthony T; Banfield, Jillian F; Doudna, Jennifer A.

Mol Cell ; 73(4): 727-737.e3, 2019 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-30709710

12.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Olenchock, Benjamin A; Moslehi, Javid; Baik, Alan H; Davidson, Shawn M; Williams, Jeremy; Gibson, William J; Chakraborty, Abhishek A; Pierce, Kerry A; Miller, Christine M; Hanse, Eric A; Kelekar, Ameeta; Sullivan, Lucas B; Wagers, Amy J; Clish, Clary B; Vander Heiden, Matthew G; Kaelin, William G.

Cell ; 165(2): 497, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27058668

13.

Reduced fire severity offers near-term buffer to climate-driven declines in conifer resilience across the western United States.

Davis, Kimberley T; Robles, Marcos D; Kemp, Kerry B; Higuera, Philip E; Chapman, Teresa; Metlen, Kerry L; Peeler, Jamie L; Rodman, Kyle C; Woolley, Travis; Addington, Robert N; Buma, Brian J; Cansler, C Alina; Case, Michael J; Collins, Brandon M; Coop, Jonathan D; Dobrowski, Solomon Z; Gill, Nathan S; Haffey, Collin; Harris, Lucas B; Harvey, Brian J; Haugo, Ryan D; Hurteau, Matthew D; Kulakowski, Dominik; Littlefield, Caitlin E; McCauley, Lisa A; Povak, Nicholas; Shive, Kristen L; Smith, Edward; Stevens, Jens T; Stevens-Rumann, Camille S; Taylor, Alan H; Tepley, Alan J; Young, Derek J N; Andrus, Robert A; Battaglia, Mike A; Berkey, Julia K; Busby, Sebastian U; Carlson, Amanda R; Chambers, Marin E; Dodson, Erich Kyle; Donato, Daniel C; Downing, William M; Fornwalt, Paula J; Halofsky, Joshua S; Hoffman, Ashley; Holz, Andrés; Iniguez, Jose M; Krawchuk, Meg A; Kreider, Mark R; Larson, Andrew J.

Proc Natl Acad Sci U S A ; 120(11): e2208120120, 2023 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-36877837

14.

A platform for distributed production of synthetic nitrated proteins in live bacteria.

Butler, Neil D; Sen, Sabyasachi; Brown, Lucas B; Lin, Minwei; Kunjapur, Aditya M.

Nat Chem Biol ; 19(7): 911-920, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37188959

15.

Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors.

Liu, Jun-Jie; Orlova, Natalia; Oakes, Benjamin L; Ma, Enbo; Spinner, Hannah B; Baney, Katherine L M; Chuck, Jonathan; Tan, Dan; Knott, Gavin J; Harrington, Lucas B; Al-Shayeb, Basem; Wagner, Alexander; Brötzmann, Julian; Staahl, Brett T; Taylor, Kian L; Desmarais, John; Nogales, Eva; Doudna, Jennifer A.

Nature ; 568(7752): E8-E10, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30944483

16.

CasX enzymes comprise a distinct family of RNA-guided genome editors.

Liu, Jun-Jie; Orlova, Natalia; Oakes, Benjamin L; Ma, Enbo; Spinner, Hannah B; Baney, Katherine L M; Chuck, Jonathan; Tan, Dan; Knott, Gavin J; Harrington, Lucas B; Al-Shayeb, Basem; Wagner, Alexander; Brötzmann, Julian; Staahl, Brett T; Taylor, Kian L; Desmarais, John; Nogales, Eva; Doudna, Jennifer A.

Nature ; 566(7743): 218-223, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30718774

17.

Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.

Klemm, Bradley P; Singh, Deepa; Smith, Cassandra E; Hsu, Allen L; Dillard, Lucas B; Krahn, Juno M; London, Robert E; Mueller, Geoffrey A; Borgnia, Mario J; Schaaper, Roel M.

Proc Natl Acad Sci U S A ; 119(37): e2123092119, 2022 09 13.

Artigo em Inglês | MEDLINE | ID: mdl-36067314

18.

Potassium levels in women with polycystic ovary syndrome using spironolactone for long-term.

deOliveira, Thais A; Marchesan, Lucas B; Spritzer, Poli M.

Clin Endocrinol (Oxf) ; 100(3): 278-283, 2024 03.

Artigo em Inglês | MEDLINE | ID: mdl-38127445

19.

High starch intake favours body weight control in neutered and spayed cats living in homes fed ad libitum.

Goloni, Camila; Pacheco, Letícia G; Luis, Letícia W; Theodoro, Stephanie S; Scarpim, Lucas B; Dalpubel, Daniela; Rosenburg, Meire Gallo; Jeusette, Isabelle C; Torre, Celina; Pereira, Gener T; Carciofi, Aulus C.

Br J Nutr ; 131(10): 1786-1802, 2024 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-38291971

20.

Evaluation of the quality and the productivity of neuroradiological reading of multiple sclerosis follow-up MRI scans using an intelligent automation software.

Federau, Christian; Hainc, Nicolin; Edjlali, Myriam; Zhu, Guangming; Mastilovic, Milica; Nierobisch, Nathalie; Uhlemann, Jan-Philipp; Paganucci, Silvio; Granziera, Cristina; Heinzlef, Olivier; Kipp, Lucas B; Wintermark, Max.

Neuroradiology ; 66(3): 361-369, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38265684

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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks.

Metabolic Frugality Marks Cancer Cells for Immune Targeting.

A Broad-Spectrum Inhibitor of CRISPR-Cas9.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

Increased demand for NAD⁺ relative to ATP drives aerobic glycolysis.

A non-canonical tricarboxylic acid cycle underlies cellular identity.

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.

A scoutRNA Is Required for Some Type V CRISPR-Cas Systems.

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.

A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Reduced fire severity offers near-term buffer to climate-driven declines in conifer resilience across the western United States.

A platform for distributed production of synthetic nitrated proteins in live bacteria.

Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors.

CasX enzymes comprise a distinct family of RNA-guided genome editors.

Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.

Potassium levels in women with polycystic ovary syndrome using spironolactone for long-term.

High starch intake favours body weight control in neutered and spayed cats living in homes fed ad libitum.

Evaluation of the quality and the productivity of neuroradiological reading of multiple sclerosis follow-up MRI scans using an intelligent automation software.