Detalhe da pesquisa
1.
Comprehensive transcriptomics and metabolomics analyses reveal that hyperhomocysteinemia is a high risk factor for coronary artery disease in a chinese obese population aged 40-65: a prospective cross-sectional study.
Cardiovasc Diabetol
; 22(1): 219, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37620823
2.
Puerarin ameliorated pressure overload-induced cardiac hypertrophy in ovariectomized rats through activation of the PPARα/PGC-1 pathway.
Acta Pharmacol Sin
; 42(1): 55-67, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504066
3.
Contributions of Nrf2 to Puerarin Prevention of Cardiac Hypertrophy and its Metabolic Enzymes Expression in Rats.
J Pharmacol Exp Ther
; 366(3): 458-469, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945930
4.
MicroRNA-26 was decreased in rat cardiac hypertrophy model and may be a promising therapeutic target.
J Cardiovasc Pharmacol
; 62(3): 312-9, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719092
5.
UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for puerarin metabolism in human liver microsomes.
Arch Toxicol
; 86(11): 1681-90, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22648071
6.
Aspirin-omitted dual antithrombotic therapy in non-valvular atrial fibrillation patients presenting with acute coronary syndrome or undergoing percutaneous coronary intervention: results of a meta-analysis.
Eur Heart J Cardiovasc Pharmacother
; 7(3): 218-224, 2021 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32129850
7.
Azilsartan ameliorates ventricular hypertrophy in rats suffering from pressure overload-induced cardiac hypertrophy by activating the Keap1-Nrf2 signalling pathway.
J Pharm Pharmacol
; 73(12): 1715-1725, 2021 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343333
8.
[Molecular mechanism of protective effect of puerarin solid lipid nanoparticle on cerebral ischemia-reperfusion injury in gerbils].
Zhong Yao Cai
; 33(12): 1900-4, 2010 Dec.
Artigo
em Zh
| MEDLINE | ID: mdl-21548369
9.
Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats.
Front Pharmacol
; 9: 540, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29928229
10.
Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro.
Front Pharmacol
; 8: 984, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29375383
11.
Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress.
Naunyn Schmiedebergs Arch Pharmacol
; 390(5): 535-545, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28210753
12.
Impact of Timing following Acute Myocardial Infarction on Efficacy and Safety of Bone Marrow Stem Cells Therapy: A Network Meta-Analysis.
Stem Cells Int
; 2016: 1031794, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26783397
13.
Effectiveness and safety of selected bone marrow stem cells on left ventricular function in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials.
Int J Cardiol
; 177(3): 764-70, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25465825
14.
Metabolic profile of puerarin in rats after intragastric administration of puerarin solid lipid nanoparticles.
Int J Nanomedicine
; 8: 933-40, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23486407
15.
Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration.
Int J Pharm
; 410(1-2): 138-44, 2011 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21392565
16.
Determination of puerarin in rat plasma by rapid resolution liquid chromatography tandem mass spectrometry in positive ionization mode.
J Chromatogr B Analyt Technol Biomed Life Sci
; 879(19): 1497-501, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21511546
17.
Metabolites of puerarin identified by liquid chromatography tandem mass spectrometry: similar metabolic profiles in liver and intestine of rats.
J Chromatogr B Analyt Technol Biomed Life Sci
; 878(3-4): 363-70, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20006564