Detalhe da pesquisa
1.
p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway.
J Cell Biol
; 177(6): 1119-32, 2007 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17576803
2.
Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability.
J Biol Chem
; 285(44): 33614-22, 2010 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20732872
3.
PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.
J Cell Biol
; 175(3): 441-51, 2006 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17088426
4.
EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.
Proc Natl Acad Sci U S A
; 105(35): 12791-6, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18728186
5.
In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10).
Cell Signal
; 20(11): 2071-83, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18721873
6.
Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.
Biochem J
; 394(Pt 2): 427-35, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16356165
7.
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.
Biochem J
; 398(1): 23-36, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16689683
8.
Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice.
FEBS Lett
; 580(17): 4126-30, 2006 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16828089
9.
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
Cell Signal
; 17(9): 1158-73, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15905070
10.
Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene.
Biochem J
; 380(Pt 2): 371-84, 2004 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15025561
11.
The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner.
FEMS Microbiol Lett
; 241(1): 109-17, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15556717
12.
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization.
J Biol Chem
; 284(17): 11425-35, 2009 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19153083
13.
Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration.
J Biol Chem
; 283(34): 22952-61, 2008 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18567578
14.
Dynamic regulation, desensitization, and cross-talk in discrete subcellular microdomains during beta2-adrenoceptor and prostanoid receptor cAMP signaling.
J Biol Chem
; 282(47): 34235-49, 2007 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17855344
15.
Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling.
Curr Top Dev Biol
; 75: 225-59, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16984814
16.
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.
J Biol Chem
; 280(39): 33178-89, 2005 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16030021
17.
The regulation of biofilm development by quorum sensing in Aeromonas hydrophila.
Environ Microbiol
; 4(1): 18-28, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11966822