Detalhe da pesquisa
1.
Subacute administration of both methcathinone and manganese causes basal ganglia damage in mice resembling that in methcathinone abusers.
J Neural Transm (Vienna)
; 127(5): 707-714, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31786692
2.
Delayed O-methylation of l-DOPA in MB-COMT-deficient mice after oral administration of l-DOPA and carbidopa.
Xenobiotica
; 48(4): 325-331, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28375049
3.
The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Neurobiol Dis
; 68: 1-15, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24746855
4.
The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson's Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On.
Neurol Ther
; 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38809484
5.
Are transglutaminase 2 inhibitors able to reduce gliadin-induced toxicity related to celiac disease? A proof-of-concept study.
J Clin Immunol
; 33(1): 134-42, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22878839
6.
Strong preferences of dopamine and l-dopa towards lipid head group: importance of lipid composition and implication for neurotransmitter metabolism.
J Neurochem
; 122(4): 681-90, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22650805
7.
Catechol-O-methyltransferase gene polymorphism and chronic human pain: a systematic review and meta-analysis.
Pharmacogenet Genomics
; 22(9): 673-91, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22722321
8.
Minocycline protects SH-SY5Y cells from 6-hydroxydopamine by inhibiting both caspase-dependent and -independent programmed cell death.
J Neurosci Res
; 90(3): 682-90, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22108958
9.
Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice.
Hum Mol Genet
; 18(20): 3914-25, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19617637
10.
Sequential expression, activity and nuclear localization of prolyl oligopeptidase protein in the developing rat brain.
Dev Neurosci
; 33(1): 38-47, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21160163
11.
Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice.
J Neurochem
; 113(6): 1632-43, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20374420
12.
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice.
J Neurochem
; 114(6): 1745-55, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20626558
13.
Are genetic variants of COMT associated with addiction?
Pharmacogenet Genomics
; 20(12): 717-41, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20975619
14.
Sample purification improves the analysis of nonviral in vivo gene transfection.
Plasmid
; 63(1): 27-30, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770000
15.
Issues about the physiological functions of prolyl oligopeptidase based on its discordant spatial association with substrates and inconsistencies among mRNA, protein levels, and enzymatic activity.
J Histochem Cytochem
; 57(9): 831-48, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19687473
16.
The role of PEI structure and size in the PEI/liposome-mediated synergism of gene transfection.
Plasmid
; 61(1): 15-21, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18804489
17.
Combination of snap freezing, differential pH two-dimensional reverse-phase high-performance liquid chromatography, and iTRAQ technology for the peptidomic analysis of the effect of prolyl oligopeptidase inhibition in the rat brain.
Anal Biochem
; 393(1): 80-7, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19539595
18.
Localization of prolyl oligopeptidase in the thalamic and cortical projection neurons: a retrograde neurotracing study in the rat brain.
Neurosci Lett
; 450(2): 201-5, 2009 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19041368
19.
Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum.
J Neurosci
; 27(38): 10196-209, 2007 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17881525
20.
Characterization of membrane-bound prolyl endopeptidase from brain.
FEBS J
; 275(17): 4415-27, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18657187