Detalhe da pesquisa
1.
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.
Proc Natl Acad Sci U S A
; 117(50): 32105-32113, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33239446
2.
Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.
PLoS Biol
; 17(5): e3000245, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086360
3.
Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aß Generation and Amyloid Plaque Pathogenesis.
J Neurosci
; 35(35): 12137-51, 2015 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338325
4.
Enhancing astrocytic lysosome biogenesis facilitates Aß clearance and attenuates amyloid plaque pathogenesis.
J Neurosci
; 34(29): 9607-20, 2014 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25031402
5.
Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury.
Circulation
; 125(25): 3170-81, 2012 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22592897
6.
Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury.
JACC Basic Transl Sci
; 8(3): 340-355, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034289
7.
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure.
JACC Basic Transl Sci
; 7(12): 1214-1228, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36644282
8.
Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease.
J Clin Invest
; 132(11)2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511433
9.
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.
JACC Basic Transl Sci
; 7(3): 223-243, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411325
10.
A self-inactivating gamma-retroviral vector reduces manifestations of mucopolysaccharidosis I in mice.
Mol Ther
; 18(2): 334-42, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19844196
11.
Morphology and genome of Euproctis pseudoconspersa nucleopolyhedrovirus.
Virus Genes
; 38(3): 495-506, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19347664
12.
Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization.
J Am Heart Assoc
; 8(4): e010866, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773991
13.
Improved retroviral vector design results in sustained expression after adult gene therapy in mucopolysaccharidosis I mice.
J Gene Med
; 10(9): 972-82, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18613275
14.
Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice.
Mol Genet Metab
; 94(3): 298-304, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18479957
15.
Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor.
Circ Heart Fail
; 10(12)2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203562
16.
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.
Autophagy
; 13(11): 1952-1968, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28853981
17.
Morphological, phylogenetic and biological characteristics of Ectropis obliqua single-nucleocapsid nucleopolyhedrovirus.
J Microbiol
; 44(1): 77-82, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16554721
18.
Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter.
Biochem J
; 388(Pt 3): 913-20, 2005 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15702971
19.
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Cell Metab
; 24(1): 158-66, 2016 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27374498
20.
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Sci Signal
; 8(382): ra62, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26106220