Detalhe da pesquisa
1.
Inhibitory effect of Porphyromonas gingivalis-derived phosphoethanolamine dihydroceramide on acid ceramidase expression in oral squamous cells.
J Cell Mol Med
; 27(9): 1290-1295, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37016912
2.
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Bioorg Chem
; 139: 106747, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531819
3.
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase.
J Lipid Res
; 63(1): 100154, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838542
4.
Knockdown of sphingomyelinase (NlSMase) causes ovarian malformation of brown planthopper, Nilaparvata lugens (Stål).
Insect Mol Biol
; 31(4): 391-402, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156743
5.
Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation.
FASEB J
; 35(2): e21284, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484475
6.
Manifold Roles of Ceramide Metabolism in Non-Alcoholic Fatty Liver Disease and Liver Cancer.
Adv Exp Med Biol
; 1372: 157-168, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35503180
7.
Maternal and fetal alkaline ceramidase 2 is required for placental vascular integrity in mice.
FASEB J
; 34(11): 15252-15268, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959379
8.
Transcriptional changes revealed genes and pathways involved in the deficient testis caused by the inhibition of alkaline ceramidase (Dacer) in Drosophila melanogaster.
Arch Insect Biochem Physiol
; 106(3): e21765, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33590535
9.
Correction: Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.
PLoS Genet
; 14(1): e1007190, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29360825
10.
Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice.
J Am Soc Nephrol
; 30(12): 2322-2336, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558682
11.
New fluorogenic probes for neutral and alkaline ceramidases.
J Lipid Res
; 60(6): 1174-1181, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926626
12.
Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates.
FASEB J
; 32(6): 3058-3069, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401619
13.
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.
PLoS Genet
; 11(10): e1005591, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474409
14.
Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications.
Hum Mutat
; 38(4): 365-372, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28181337
15.
Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy.
J Med Genet
; 53(6): 389-96, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26792856
16.
Rice Stripe Virus Infection Alters mRNA Levels of Sphingolipid-Metabolizing Enzymes and Sphingolipids Content in Laodelphax striatellus.
J Insect Sci
; 17(1)2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28130458
17.
Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death.
J Biol Chem
; 290(42): 25356-73, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26318452
18.
Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.
J Lipid Res
; 56(10): 2019-28, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26286360
19.
Glucosylceramides are required for mycelial growth and full virulence in Penicillium digitatum.
Biochem Biophys Res Commun
; 455(3-4): 165-71, 2014 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25449268
20.
Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.
Bioorg Med Chem
; 22(24): 6933-44, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25456083