Detalhe da pesquisa
1.
Polyploidisation pleiotropically buffers ageing in hepatocytes.
J Hepatol
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583492
2.
Advances of single-cell genomics and epigenomics in human disease: where are we now?
Mamm Genome
; 31(5-6): 170-180, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32270277
3.
Spatial transcriptomics using multiplexed deterministic barcoding in tissue.
Nat Commun
; 14(1): 1523, 2023 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36934108
4.
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.
Cell Rep
; 42(10): 113305, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37864798
5.
Isolation of Nuclei from Flash-frozen Liver Tissue for Single-cell Multiomics.
J Vis Exp
; (190)2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36571404
6.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Mol Metab
; 60: 101487, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378329
7.
Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis.
Nat Commun
; 10(1): 1251, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890697
8.
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
Curr Drug Metab
; 8(2): 185-94, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17305497
9.
Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP).
BMJ Open
; 7(3): e014931, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28302638
10.
Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.
ACS Chem Biol
; 12(3): 654-663, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28059499
11.
Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.
Expert Opin Drug Metab Toxicol
; 2(2): 183-212, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16866607
12.
Epigenetic crosstalk: a molecular language in human metabolic disorders.
Front Biosci (Schol Ed)
; 7(1): 46-57, 2015 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25961686
13.
Can hepatoma cell lines be redifferentiated to be used in drug metabolism studies?
Altern Lab Anim
; 32 Suppl 1A: 65-74, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23577436
14.
Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex.
FEBS Open Bio
; 4: 996-1006, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25473596
15.
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.
Science
; 328(5981): 1036-40, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20378774
16.
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
Mol Pharmacol
; 70(5): 1681-92, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16882880
17.
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
J Biol Chem
; 281(40): 29840-9, 2006 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16891307
18.
Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein).
Mol Pharmacol
; 67(6): 2088-101, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15778453