Detalhe da pesquisa
1.
Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease.
Kidney Int
; 104(5): 995-1007, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37598857
2.
Variants in FtsJ RNA 2'-O-Methyltransferase 3 and Growth Hormone 1 are associated with small body size and a dental anomaly in dogs.
Proc Natl Acad Sci U S A
; 117(40): 24929-24935, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958658
3.
Chromosome ends as adaptive beginnings: the potential role of dysfunctional telomeres in subtelomeric evolvability.
Curr Genet
; 64(5): 997-1000, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29589105
4.
Caffeine inhibits gene conversion by displacing Rad51 from ssDNA.
Nucleic Acids Res
; 43(14): 6902-18, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26019181
5.
Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2.
Nucleic Acids Res
; 43(14): 6889-901, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26019182
6.
RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.
Nucleic Acids Res
; 43(6): 3180-96, 2015 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25765654
7.
The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.
Hum Mol Genet
; 22(24): 4901-13, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863462
8.
FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe.
DNA Repair (Amst)
; 133: 103611, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38103522
9.
Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks.
Hum Mol Genet
; 20(13): 2549-59, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478198
10.
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Bioorg Med Chem
; 21(17): 5629-46, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23810424
11.
FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe.
bioRxiv
; 2023 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292855
12.
UBC13-mediated template switching promotes replication stress resistance in FBH1-deficient cells.
bioRxiv
; 2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37732269
13.
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.
Bioorg Med Chem
; 20(17): 5181-7, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22854195
14.
The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms.
Cancer Res
; 81(6): 1540-1551, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472891
15.
Reducing the Toxicity of Designer Aminoglycosides as Nonsense Mutation Readthrough Agents for Therapeutic Targets.
ACS Med Chem Lett
; 12(9): 1486-1492, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34531957
16.
Ethyl 1-benzyl-4-hydr-oxy-2-methyl-5-oxopyrrolidine-3-carboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 4): o957, 2010 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21580760
17.
Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase.
Biochemistry
; 48(23): 5226-38, 2009 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19425594
18.
Large P body-like RNPs form in C. elegans oocytes in response to arrested ovulation, heat shock, osmotic stress, and anoxia and are regulated by the major sperm protein pathway.
Dev Biol
; 318(1): 38-51, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18439994
19.
Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities?
Bioorg Med Chem
; 17(19): 6898-907, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19744859
20.
7-Benzyl-oxymethyl-9-bromo-6-chloro-9-deaza-purine.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 1): o138, 2009 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21580029