Detalhe da pesquisa
1.
Autotrophic and Heterotrophic Growth Conditions Modify Biomolecole Production in the Microalga Galdieria sulphuraria (Cyanidiophyceae, Rhodophyta).
Mar Drugs
; 18(3)2020 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32197552
2.
Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923.
Int J Mol Sci
; 21(16)2020 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781637
3.
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality.
Nucleic Acids Res
; 45(14): 8156-8166, 2017 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666330
4.
The "Janus face" of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications.
Bioorg Chem
; 76: 202-209, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190476
5.
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs.
Mar Drugs
; 16(3)2018 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534435
6.
Synthesis and label free characterization of a bimolecular PNA homo quadruplex.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1222-1228, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913190
7.
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.
Nucleic Acids Res
; 43(16): 7702-16, 2015 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26250112
8.
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity.
Nucleic Acids Res
; 43(22): 10602-11, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582916
9.
Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques.
Anal Chem
; 88(4): 2327-34, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26810800
10.
New synthetic AICAR derivatives with enhanced AMPK and ACC activation.
J Enzyme Inhib Med Chem
; 31(5): 748-53, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446934
11.
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures.
Org Biomol Chem
; 13(27): 7421-9, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25997822
12.
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue.
Chembiochem
; 15(5): 652-5, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24520055
13.
5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification.
Chembiochem
; 15(16): 2427-34, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25214456
14.
More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures.
Org Biomol Chem
; 12(3): 534-40, 2014 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24287516
15.
A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance.
Org Biomol Chem
; 12(44): 8840-3, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25296283
16.
The insertion of two 8-methyl-2'-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands.
Nucleic Acids Res
; 40(1): 461-75, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908403
17.
d(CGGTGGT) forms an octameric parallel G-quadruplex via stacking of unusual G(:C):G(:C):G(:C):G(:C) octads.
Nucleic Acids Res
; 39(17): 7848-57, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21715378
18.
Synthesis of new acadesine (AICA-riboside) analogues having acyclic D-ribityl or 4-hydroxybutyl chains in place of the ribose.
Molecules
; 18(8): 9420-31, 2013 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23924994
19.
Structural investigations on the anti-HIV G-quadruplex-forming oligonucleotide TGGGAG and its analogues: evidence for the presence of an A-tetrad.
Chembiochem
; 13(15): 2219-24, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22945376
20.
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures.
Nucleic Acids Res
; 38(6): 2069-80, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20026588