Detalhe da pesquisa
1.
Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16.
PLoS Genet
; 14(9): e1007664, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30222779
2.
Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP.
Hum Mol Genet
; 23(4): 1013-24, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24113144
3.
Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise.
Cell Biochem Funct
; 31(8): 724-35, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23553918
4.
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70.
Nature
; 440(7083): 551-5, 2006 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16554822
5.
Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.
J Biol Chem
; 284(31): 20649-59, 2009 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-19465479
6.
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.
J Clin Invest
; 117(11): 3211-23, 2007 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17965779
7.
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.
J Cell Biol
; 171(6): 925-30, 2005 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16344307
8.
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy.
J Cell Biol
; 167(6): 1147-59, 2004 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15596539
9.
PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation.
J Mol Cell Cardiol
; 44(1): 47-58, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17662997
10.
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex.
J Clin Invest
; 114(8): 1058-71, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15489953
11.
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.
J Clin Invest
; 132(1)2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34981792
12.
CHIP: a link between the chaperone and proteasome systems.
Cell Stress Chaperones
; 8(4): 303-8, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115282
13.
The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination.
Mol Cell Biol
; 33(22): 4461-72, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043303
14.
Regulation of the cytoplasmic quality control protein degradation pathway by BAG2.
J Biol Chem
; 280(46): 38673-81, 2005 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16169850
15.
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.
Proc Natl Acad Sci U S A
; 101(52): 18135-40, 2004 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-15601779
16.
CHIP activates HSF1 and confers protection against apoptosis and cellular stress.
EMBO J
; 22(20): 5446-58, 2003 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14532117