Detalhe da pesquisa
1.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Cell
; 185(4): 614-629.e21, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148840
2.
SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis.
Proc Natl Acad Sci U S A
; 119(37): e2204717119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040867
3.
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
J Allergy Clin Immunol
; 152(5): 1107-1120.e6, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595760
4.
The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.
Proc Natl Acad Sci U S A
; 117(48): 30687-30698, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184176
5.
SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection.
mBio
; 14(4): e0119423, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377442
6.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
bioRxiv
; 2023 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36238716
7.
Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants.
Nat Commun
; 14(1): 1130, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854666
8.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
Nat Commun
; 14(1): 3026, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37230979
9.
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice.
NPJ Vaccines
; 8(1): 18, 2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788219
10.
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
bioRxiv
; 2022 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36523401
11.
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19.
Commun Biol
; 5(1): 808, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35962188
12.
The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo.
Res Sq
; 2022 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36597547
13.
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant.
Commun Biol
; 5(1): 790, 2022 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933439
14.
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.
Sci Transl Med
; 14(629): eabj5305, 2022 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783582
15.
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Nat Microbiol
; 6(10): 1233-1244, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548634
16.
Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination.
Cell Rep Med
; 2(9): 100405, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34485950
17.
Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
bioRxiv
; 2021 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33564763
18.
Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity.
bioRxiv
; 2021 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031655
19.
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Nat Commun
; 12(1): 6055, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663813
20.
Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.
bioRxiv
; 2021 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32935104