RESUMO
The research deals with the effect of low-intensity 900 MHz frequency electromagnetic radiation (EMR), power density 25 µW/cm2, on the following rat brain and blood serum enzyme activities: creatine kinase (CK), playing a central role in the process of storing and distributing the cell energy, as well as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) that play a key role in providing the conjunction of carbohydrate and amino acid metabolism. The comparative analysis of the changes in the enzyme activity studied at different times following the two-hour single, as well as fractional, radiation equivalent of the total time showed that the most radiosensitive enzyme is the brain creatine kinase, which may then be recommended as a marker of the radio frequency radiation impact. According to the analysis of the changing dynamics of the CK, ALT and AST activity level, with time these changes acquire the adaptive character and are directed to compensate the damaged cell energy metabolism.
Assuntos
Alanina Transaminase/metabolismo , Aspartato Aminotransferases/metabolismo , Encéfalo/efeitos da radiação , Creatina Quinase/metabolismo , Radiação Eletromagnética , Metabolismo Energético/efeitos da radiação , Adaptação Fisiológica , Alanina Transaminase/sangue , Animais , Aspartato Aminotransferases/sangue , Encéfalo/enzimologia , Encéfalo/metabolismo , Creatina Quinase/sangue , Relação Dose-Resposta à Radiação , Masculino , Ratos , Irradiação Corporal TotalRESUMO
INTRODUCTION: In third cranial nerve palsy, the lack of mydriasis evokes a noncompressive mechanism. Case report. We report a case of a slightly painful, pure extrinsic third-nerve palsy, complete except for the partial ptosis secondary to the compression by an intracavernous carotid aneurysm. Percutaneous endovascular embolization was followed by complete regression of the palsy within 4 weeks. The pupil may have been spared by the mechanism of compression after the separation of the pupillomotor and extrinsic fibers or the ischemia of the third nerve by its arterial trunk lesion. CONCLUSION: This case report underlines that brain radiological explorations are necessary in some third-nerve pupil-sparing palsies.