Lattice QCD Matrix Elements for the B_{s}

Predicting the B_{s}^{0}-B[over ¯]_{s}^{0} width difference ΔΓ_{s} relies on the heavy quark expansion and on hadronic matrix elements of ΔB=2 operators. We present the first lattice QCD results for matrix elements of the dimension-7 operators R_{2,3} and linear combinations R[over ˜]_{2,3} using nonrelativistic QCD for the bottom quark and a highly improved staggered quark (HISQ) action for the strange quark. Computations use MILC Collaboration ensembles of gauge field configurations with 2+1+1 flavors of sea quarks with the HISQ discretization, including lattices with physically light up or down quark masses. We discuss features unique to calculating matrix elements of these operators and analyze uncertainties from series truncation, discretization, and quark mass dependence. Finally we report the first standard model determination of ΔΓ_{s} using lattice QCD results for all hadronic matrix elements through O(1/m_{b}). The main result of our calculations yields the 1/m_{b} contribution ΔΓ_{1/m_{b}}=-0.022(10) ps^{-1}. Adding this to the leading order contribution, the standard model prediction is ΔΓ_{s}=0.092(14) ps^{-1}.

Hydrodynamic fluctuation-induced forces in confined fluids.

We study thermal, fluctuation-induced hydrodynamic interaction forces in a classical, compressible, viscous fluid confined between two rigid, planar walls with no-slip boundary conditions. We calculate hydrodynamic fluctuations using the linearized, stochastic Navier-Stokes formalism of Landau and Lifshitz. The mean fluctuation-induced force acting on the fluid boundaries vanishes in this system, so we evaluate the two-point, time-dependent force correlations. The equal-time correlation function of the forces acting on a single wall gives the force variance, which we show to be finite and independent of the plate separation at large inter-plate distances. The equal-time, cross-plate force correlation, on the other hand, decays with the inverse inter-plate distance and is independent of the fluid viscosity at large distances; it turns out to be negative over the whole range of plate separations, indicating that the two bounding plates are subjected to counter-phase correlations. We show that the time-dependent force correlations exhibit damped temporal oscillations for small plate separations and a more irregular oscillatory behavior at large separations. The long-range hydrodynamic correlations reported here represent a "secondary Casimir effect", because the mean fluctuation-induced force, which represents the primary Casimir effect, is absent.

Brief Intervention to Reduce Hazardous Drinking and Enhance Coping among OEF/OIF/OND Veterans.

Hazardous drinking among US Military combat veterans is an important public health issue. Because recent combat veterans are difficult to engage in specialty mental health and substance abuse care, there is a need for opportunistic interventions administered in settings visited by recent combat veterans such as primary care. This paper describes a brief (single-session) intervention that was recently developed and tested in a sample of veterans of Operations Enduring Freedom, Iraqi Freedom and New Dawn (OEF/OIF/OND). The intervention consists of a counseling session delivered in a Motivational Interviewing style using a packet of personalized feedback about alcohol misuse, symptoms of PTSD and depression, as well as coping skills. The treatment is described and data from a single case treated with this intervention are presented.

Drinking motives among heavy-drinking veterans with and without posttraumatic stress disorder.

OBJECTIVE: This study examined patterns of drinking motives endorsed by heavy drinking veterans who either did or did not meet criteria for posttraumatic stress disorder (PTSD). METHOD: Data were collected from 69 veterans of Operations Enduring Freedom or Iraqi Freedom (OEF/OIF) who had screened positive for hazardous drinking. The sample was 91.3% male and 65.2% Caucasian. Based on a structured interview, 58% of the sample met criteria for PTSD. RESULTS: The PTSD group scored higher than the non-PTSD group on scales measuring drinking to cope with anxiety and depression and similarly to the non-PTSD group on scales measuring social, enhancement and conformity motives. Coping and social motives were significantly correlated with adverse alcohol consequences. Overall, the PTSD group showed stronger relations between coping scales and aspects of alcohol misuse, relative to the non- PTSD group. CONCLUSION: These findings suggest first, that among heavy drinking OEF/OIF veterans there is a high base rate of PTSD. Second, coping motives are frequently reported in this population, and they seem to be related to a more severe pattern of alcohol-related consequences. These findings underscore the importance of assessing the interplay between PTSD and substance abuse in trauma-exposed samples.

Standard model predictions for B→Kℓ(+)ℓ- with form factors from lattice QCD.

We calculate, for the first time using unquenched lattice QCD form factors, the standard model differential branching fractions dB/dq2(B→Kℓ(+)ℓ(-)) for ℓ=e, µ, τ and compare with experimental measurements by Belle, BABAR, CDF, and LHCb. We report on B(B→Kℓ(+)ℓ(-)) in q2 bins used by experiment and predict B(B→Kτ(+)τ(-))=(1.41±0.15)×10(-7). We also calculate the ratio of branching fractions R(e)(µ)=1.00029(69) and predict R(ℓ)(τ)=1.176(40), for ℓ=e, µ. Finally, we calculate the "flat term" in the angular distribution of the differential decay rate F(H)(e,µ,τ) in experimentally motivated q2 bins.

PTSD symptoms, hazardous drinking, and health functioning among U.S.OEF and OIF veterans presenting to primary care.

Posttraumatic stress disorder (PTSD) and alcohol abuse both are negatively associated with health, and alcohol misuse may mediate the relationship between PTSD and functional health outcomes. The present study tested for such mediation using self-report measures of PTSD symptoms, hazardous alcohol use, and health functioning in 151 U.S. veterans (136 men and 15 women) of the wars in Iraq and Afghanistan recruited from a Veterans Affairs primary care clinic. Based on established cut scores, 39.1% screened positive for PTSD and 26.5% screened positive for hazardous drinking. PTSD symptoms and hazardous drinking were significantly correlated with each other and with health functioning. Hazardous drinking was found to partially mediate the relationship between PTSD and functional mental health, but not physical health.

Unique Patterns of Substance Misuse associated with PTSD, Depression, and Social Phobia.

OBJECTIVES: This study investigated the relations between post-trauma psychopathology and substance abuse in a sample of trauma-exposed college students (n = 136) assigned to four groups based on primary diagnosis: posttraumatic stress disorder, depression, social phobia, or well-adjusted (participants who had low levels of distress). Groups were compared on a series of dimensions of substance use/abuse. RESULTS: Participants in the PTSD group evidenced greater substance use and abuse than those in the social phobia and well-adjusted groups on several dimensions and greater alcohol consumption than the depressed group. Correlation analyses suggested that most dimensions of substance abuse were related more strongly to avoidance and numbing (cluster C) symptoms than to reexperiencing and hyperarousal. CONCLUSIONS: The present findings suggest that trauma-related psychopathology may be associated with a more hazardous pattern of substance use than depression and social phobia.

Mental health utilization among veterans at risk for suicide: Data from a post-deployment clinic.

The current study aim was to examine mental health characteristics in a sample of returning OEF/OIF/OND veterans initially enrolling in Department of Veterans Affairs (VA) health care (N = 1,307), with a particular focus on a subgroup considered at risk for suicide (N = 445). Methods included examination of mental health screening measures and clinical interview data from a VA postdeployment clinic. Half of the sample met criteria for a mental health disorder, whereas 10% reported current suicidal or death ideation (e.g., thoughts of being better off dead or hurting oneself in some way) and 6% reported a history of suicide attempt. Sixty-eight percent of the at-risk subgroup accepted a referral for mental health treatment and a promising majority (78%) of those individuals attended their initial specialty mental health visit. At-risk veterans who accepted mental health referral were more likely to report current suicidal/death ideation; they were also more likely to have a diagnosis of a depressive disorder, anxiety disorder, or posttraumatic stress disorder. Factors associated with mental health appointment attendance included older age, being enrolled in college, and more years of military service. Results highlight the importance of early screening and referral to appropriate mental health follow-up. Implications for clinical practice and increasing engagement in VA mental health services among veterans at risk for suicide are discussed. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Improved Patient Outcomes and Reduced Wait Times: Transforming a VA Outpatient Substance Use Disorder Program.

Systematic evaluation and redesign of a substance use disorder treatment program resulted in elimination of wait times, same-day treatment, and increased pharmacotherapy for patients with alcohol and opioid use disorders.

Randomized controlled trial of two brief alcohol interventions for OEF/OIF veterans.

OBJECTIVE: The purpose of this study was to test the efficacy of 2 brief interventions for alcohol misuse in a sample of combat veterans of the wars in Iraq and Afghanistan. METHOD: Participants were 68 combat veterans (91.2% male; 64.7% White, 27.9% Black) with a mean age of 32.31 years (SD = 8.84) who screened positive for hazardous drinking in a Veterans Affairs Medical Center primary care clinic using the Alcohol Use Disorders Identification Test (Babor, Higgins-Biddle, Saunders, & Monteiro, 2001). More than half of the sample (57.4%) met criteria for posttraumatic stress disorder (PTSD; based on the Clinician-Administered PTSD Scale; Blake et al., 1995). Eligible veterans who elected to participate completed a baseline assessment and were randomized to receive 1 of 2 interventions (personalized feedback delivered with or without a motivational interviewing counseling session). Both interventions included information on hazardous drinking, PTSD symptoms, depression, and coping. Follow-up assessments were conducted at 6 weeks and 6 months post-intervention. RESULTS: Both conditions resulted in statistically significant reductions in quantity and frequency of alcohol use as well as frequency of binge drinking and alcohol-related consequences. Within-group effect sizes (ds) were in the small to medium range (.21-.55) for quantity and frequency of alcohol use. There were no statistically significant Condition × Time interactions, suggesting that both interventions were similarly effective. PTSD and non-PTSD veterans responded equally well to both interventions, but veterans with PTSD assigned to feedback plus motivational interviewing reported greater reductions in weekly drinking at the 6-week follow-up. CONCLUSIONS: These findings suggest that brief interventions for alcohol misuse may be effective for reducing drinking, even in an Operation Enduring Freedom/Operation Iraqi Freedom veteran population with a high degree of PTSD.

The impact of elevated posttraumatic stress on the efficacy of brief alcohol interventions for heavy drinking college students.

Brief alcohol interventions (BAIs) have been widely adopted for use with college students and are associated with significant reductions in drinking and problems. However, many students do not respond to these approaches and little is known about risk factors for poor response. The current study investigated one possible risk factor by examining the impact of posttraumatic stress (PTS) symptoms on BAI efficacy. This study presents pooled data from two randomized clinical trials that examined the efficacy of counselor-administered BAIs compared with computerized interventions. Participants were 207 college students (53.1% women, 68.1% White/Caucasian, 16.9% with elevated post-traumatic stress) who reported past-month heavy episodic drinking. Follow-up assessments were completed six months post-intervention. Analyses testing differences in frequency of past-month heavy episodic drinking revealed a significant post-traumatic stress by time interaction (F(1,165)=8.27, p=.005) such that individuals screening positive for PTS showed larger reductions in heavy episodic drinking at follow-up. A significant three-way interaction between time, PTS, and intervention condition (F(2,167)=5.76, p=.004) was found for alcohol related consequences. Specifically, among individuals screening positive for PTS, only those that received the counselor-administered BAI showed a significant reduction in consequences at follow-up. These results suggest that overall college students with PTS may respond well to BAIs and that counselor-delivered BAIs may be more efficacious than computer-delivered interventions for reducing alcohol problems for these high-risk students.

Health-related quality of life among heavy-drinking college students.

OBJECTIVE: To examine unique contributions of depression, alcohol consumption, and alcohol-related consequences on functional health outcomes in college students. METHODS: Participants were heavy-drinking undergraduate students (N = 207) who completed self-report questionnaires. RESULTS: For men and women, depression predicted overall general health and mental health ratings. For women, depression predicted number of days of role limitations due to poor physical or mental health and number of days of not getting enough sleep or rest. CONCLUSIONS: Findings suggest that depression may have a more pervasive association with HRQOL than alcohol misuse or alcohol-related consequences in college students.

Factor Structure of the PTSD Checklist in a Sample of OEF/OIF Veterans Presenting to Primary Care: Specific and Nonspecific Aspects of Dysphoria.

Although DSM-IV-TR diagnostic criteria for posttraumatic stress disorder (PTSD) include three primary symptom clusters, recent evidence from confirmatory factor analyses suggest that the latent structure of PTSD is better represented by four factors, which will likely be reflected in the upcoming DSM-5. Given this likely transition from three to four clusters, the present study sought to examine specific and non-specific aspects of dysphoria in the factor structure of PTSD symptoms in a sample of OEF/OIF combat veterans presenting to a Veterans Affairs primary care clinic. PTSD symptoms were assessed using the PCL-M (Weathers et al. 1993). Results from confirmatory factor analyses suggested that a dysphoria factor involving a number of non-specific distress symptoms may be an important part of the PTSD symptom profile. After controlling for variance due to general psychological distress, we further found that factor loadings on the dysphoria factor were attenuated but continued to significantly load onto the factor, suggesting that dysphoria may be a specific part of the PTSD symptom constellation.

New evidence for hominin carcass processing strategies at 1.5 Ma, Koobi Fora, Kenya.

Reconstruction of early Pleistocene hominin carcass acquisition and processing behaviors are necessarily based at least in part on butchered fossil bones. This paper provides zooarchaeological and taphonomic analyses and behavioral interpretations of three approximately 1.5 million-year-old archaeofaunas from areas 1A and 103 in the Okote Member of the Koobi Fora Formation, northern Kenya: FwJj14A, FwJj14B, and GaJi14. These sites are all located in similar paleoenvironmental contexts, near shallow water with swampy, seasonally flooded areas, and some evidence for more wooded or gallery forest settings. Both individual specimen--and assemblage-level analyses of butchery-marked bones indicate that the hominins appear to have practiced similar butchery strategies at all of these sites, with butchery (defleshing, disarticulation, and marrow extraction) of both high- and low-ranked skeletal elements with no apparent preference for prey size, skeletal region, limb class, or limb portion. Only four tooth-marked specimens, including one likely crocodile-tooth-marked bone, are preserved in all three archaeofaunas. A paucity of limb epiphyses suggests that bone-crunching hyenids may have deleted these portions subsequent to hominin butchery. Strangely, there are no stone tools preserved with the 292 cut-marked and 27 percussion-marked faunal specimens (out of a total of 6,039 specimens), suggesting that raw material availability may have conditioned hominin lithic discard patterns at these locales. These assemblages increase our knowledge of the dietary behavior and ecology of Homo erectus, and provide support for variability in early Pleistocene hominin carcass foraging patterns.