Male infant patient with a mesenteric cyst in the greater and lesser omenta: a case report.

BACKGROUND: Mesenteric cysts are intra-abdominal masses of congenital origin, which most frequently occur in children, with an incidence of approximately 1 case per 20,000 pediatric admissions. Its progression can be asymptomatic, and its diagnosis can be incidental. However, it usually occurs with symptoms such as nausea, vomiting, constipation, sensation of a mass, and/or diarrhea. The diagnostic imaging method of choice is abdominal ultrasound. CASE PRESENTATION: Below, we present the case of a previously healthy 1-year-old male patient with nonspecific symptoms, who was referred to a tertiary hospital. The presence of a mesenteric cyst was detected at the end of the diagnostic approach. CONCLUSION: It is important to know these pathologies even though they are infrequent, because although they are benign masses by definition, they can lead to complications such as intestinal torsion, intestinal obstruction, and even peritonitis.

[Acute pancreatitis secondary to an abdominal trauma: case report of a 7-year-old child]. / Pancreatitis aguda secundaria a un trauma abdominal: reporte de caso de una niña de 7 años.

Pancreatitis consists in acute inflammation of the pancreas that is clinically characterized by abdominal pain. To make the diagnosis it is necessary the elevation of biochemical markers like pancreatic amylase or lipase. It is the most frequent pancreatic disease in both children and adults. Its presentation in the pediatric population is increasing and has several etiologies such as: infections, trauma, intoxication and metabolic diseases. Trauma mechanisms have been described: child maltreatment, falls, trauma with the bicycle handle and traffic accidents. In this article, we present a case of pancreatitis secondary to an abdominal trauma with the handle of a bicycle in a patient of 7 years.

La pancreatitis consiste en la inflamación aguda del páncreas, que se caracteriza, clínicamente, por dolor abdominal. Para realizar el diagnóstico, es necesario que se presente la elevación de marcadores bioquímicos, como amilasa o lipasa pancreáticas. Esta afección es la enfermedad pancreática más frecuente tanto en niños como en adultos. Su presentación en la población pediátrica está en aumento y tiene varias etiologías, como infecciones, trauma, intoxicación y enfermedades metabólicas. Entre los mecanismos de trauma, se han descrito maltrato infantil, caídas, trauma con el manubrio de la bicicleta y accidentes de tránsito. En este artículo, se presenta un caso de pancreatitis secundaria a un trauma abdominal con el manubrio de una bicicleta en una paciente de 7 años.

GDF15(MIC1) H6D Polymorphism Does Not Influence Cardiovascular Disease in a Latin American Population with Rheumatoid Arthritis.

OBJECTIVE: Rheumatoid arthritis (RA) is the most common autoimmune arthropathy worldwide. The increased prevalence of cardiovascular disease (CVD) in RA is not fully explained by classic risk factors. The aim of this study was to determine the influence of rs1058587 SNP within GDF15(MIC1) gene on the risk of CVD in a Colombian RA population. METHODS: This was a cross-sectional analytical study in which 310 consecutive Colombian patients with RA and 228 age- and sex-matched controls were included and assessed for variables associated with CVD. The mixed cluster methodology based on multivariate descriptive methods such as principal components analysis and multiple correspondence analyses and regression tree (CART) predictive model were performed. RESULTS: Of the 310 patients, 87.4% were women and CVD was reported in 69.5%. Significant differences concerning GDF15 polymorphism were not observed between patients and controls. Mean arterial pressure, current smoking, and some clusters were significantly associated with CVD. CONCLUSION: GDF15 (rs1058587) does not influence the development of CVD in the population studied.

Cardiovascular involvement in autoimmune diseases.

Autoimmune diseases (AD) represent a broad spectrum of chronic conditions that may afflict specific target organs or multiple systems with a significant burden on quality of life. These conditions have common mechanisms including genetic and epigenetics factors, gender disparity, environmental triggers, pathophysiological abnormalities, and certain subphenotypes. Atherosclerosis (AT) was once considered to be a degenerative disease that was an inevitable consequence of aging. However, research in the last three decades has shown that AT is not degenerative or inevitable. It is an autoimmune-inflammatory disease associated with infectious and inflammatory factors characterized by lipoprotein metabolism alteration that leads to immune system activation with the consequent proliferation of smooth muscle cells, narrowing arteries, and atheroma formation. Both humoral and cellular immune mechanisms have been proposed to participate in the onset and progression of AT. Several risk factors, known as classic risk factors, have been described. Interestingly, the excessive cardiovascular events observed in patients with ADs are not fully explained by these factors. Several novel risk factors contribute to the development of premature vascular damage. In this review, we discuss our current understanding of how traditional and nontraditional risk factors contribute to pathogenesis of CVD in AD.

Pancreatitis aguda secundaria a un trauma abdominal: reporte de caso de una niña de 7 años / Acute pancreatitis secondary to an abdominal trauma: case report of a 7-year-old child

La pancreatitis consiste en la inflamación aguda del páncreas, que se caracteriza, clínicamente, por dolor abdominal. Para realizar el diagnóstico, es necesario que se presente la elevación de marcadores bioquímicos, como amilasa o lipasa pancreáticas. Esta afección es la enfermedad pancreática más frecuente tanto en niños como en adultos. Su presentación en la población pediátrica está en aumento y tiene varias etiologías, como infecciones, trauma, intoxicación y enfermedades metabólicas. Entre los mecanismos de trauma, se han descrito maltrato infantil, caídas, trauma con el manubrio de la bicicleta y accidentes de tránsito. En este artículo, se presenta un caso de pancreatitis secundaria a un trauma abdominal con el manubrio de una bicicleta en una paciente de 7 años.

Pancreatitis consists in acute inflammation of the pancreas that is clinically characterized by abdominal pain. To make the diagnosis it is necessary the elevation of biochemical markers like pancreatic amylase or lipase. It is the most frequent pancreatic disease in both children and adults. Its presentation in the pediatric population is increasing and has several etiologies such as: infections, trauma, intoxication and metabolic diseases. Trauma mechanisms have been described: child maltreatment, falls, trauma with the bicycle handle and traffic accidents. In this article, we present a case of pancreatitis secondary to an abdominal trauma with the handle of a bicycle in a patient of 7 years.