Effect of etretinate on chemotaxis of neutrophils from patients with pustular and vulgar psoriasis.

The chemotactic activities of neutrophil granulocytes of patients with pustular and vulgar psoriasis were evaluated before and after treatment with etretinate. Control values before treatment were significantly different from those of vulgar psoriasis group but not from the pustular psoriasis group. The difference between the 2 groups with psoriasis was significant. Etretinate causes a significant reduction in neutrophil chemotaxis in pustular psoriasis patients and a less pronounced reduction in those with vulgar psoriasis.

Dimensional analysis of milk fat globules in sow milk: effects of the lactation stage and fat content and comparison with vaccine milk.

To assess the differences in the granulometry of milk fat globules between swine and bovine species, milk samples from 30 lactating sows were analyzed for fat globule dimensions and compared with cow milk samples. Results showed differences between the fat globules: sow milk presents reduced globule diameters compared with cow milk (volume-weighted diameter 2.62 vs. 3.27 microm, p < 0.001) and reduced interglobular distance. A positive relationship was observed between milk fat content and globule diameter, while a slight, insignificant inverse trend was detected between the day of lactation and fat globule diameter. These complex interactions between milk lipids, globule membrane proteins, and globule dimensions provide a better understanding of digestion/absorption phenomena in the design of milk replacers.

[Treatment with levamisole in a case of deficiency of the neutrophil granulocyte function associated with an increase in plasma IgA and recurrent dermal abscess infections]. / Trattamento con Levamisolo di un caso di deficit della funzionalità dei granulociti neutrofili associato ad aumento delle IgA plasmatiche e infezioni ascessuali dermiche ricorrenti.

The authors describe a case of recurrent dermal abscess infections resistant to usual antibiotic therapy and demonstrating a failing of the activity of the neutrophils and a remarkable increase of plasmatic IgA. The treatment with Levamisole regularized the laboratory data and, as a result, determined a consequent important improvement of the patient.

Effects of isotretinoin on the neutrophil chemotaxis in cystic acne.

The authors show that the use of Isotretinoin (Ro 4-3740) in cystic acne brings a reduction of chemotactic activity of the neutrophil granulocytes, like another retinoid, Etretinate, in pustular and vulgar psoriasis. This effect of retinoids, with a direct action on the polymorphonuclear leukocytes plays an important role in the recovery of the disease.