Detalhe da pesquisa
1.
Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.
Pharmacol Res
; 109: 119-31, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26921661
2.
Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine. Impact on its function as membrane barrier.
Pharmacol Res
; 109: 32-44, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27109321
3.
Physiological concentrations of unconjugated bilirubin prevent oxidative stress-induced hepatocanalicular dysfunction and cholestasis.
Arch Toxicol
; 88(2): 501-14, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24306262
4.
Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor.
Drug Metab Dispos
; 41(2): 275-80, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23077105
5.
Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.
Drug Metab Dispos
; 40(7): 1252-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22453052
6.
Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C.
Hepatology
; 52(4): 1465-76, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20815017
7.
Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat.
J Pharmacol Exp Ther
; 335(2): 332-41, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20719938
8.
Intraluminal nutrients acutely strengthen rat intestinal MRP2 barrier function by a glucagon-like peptide-2-mediated mechanism.
Acta Physiol (Oxf)
; 230(4): e13514, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32476256
9.
Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat.
Hepatology
; 48(6): 1885-95, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18972403
10.
Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens.
Drug Metab Dispos
; 37(6): 1277-85, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19299525
11.
Complement activation and disease: protective effects of hyperbilirubinaemia.
Clin Sci (Lond)
; 118(2): 99-113, 2009 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19807696
12.
Improved hepatic MRP2/ABCC2 transport activity in LPS-induced cholestasis by aquaporin-1 gene transfer.
Biochimie
; 165: 179-182, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31377196
13.
Protective role of unconjugated bilirubin on complement-mediated hepatocytolysis.
Biochim Biophys Acta
; 1770(7): 1003-10, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17442495
14.
Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats.
Drug Metab Dispos
; 36(3): 475-80, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18096675
15.
Dapsone induces oxidative stress and impairs antioxidant defenses in rat liver.
Life Sci
; 83(5-6): 155-63, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18602405
16.
Hepatic drug transporters and nuclear receptors: regulation by therapeutic agents.
World J Gastroenterol
; 14(46): 7068-74, 2008 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19084913
17.
Dynamic localization of hepatocellular transporters in health and disease.
World J Gastroenterol
; 14(44): 6786-801, 2008 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19058304
18.
Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.
Biochem Pharmacol
; 69(3): 531-9, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15652244
19.
Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.
Toxicol Sci
; 84(1): 4-11, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15590889
20.
Dapsone impairs the bile salt-independent fraction of bile flow in rats: Possible involvement of its N-hydroxylated metabolite.
Toxicology
; 211(1-2): 97-106, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15863252