RESUMO
OBJECTIVE: To review the clinical presentation and histopathologic findings on a series of cats with orbital fibrotic disease and compare the data to that of humans with sclerosing orbital pseudotumor. ANIMALS: A retrospective study was undertaken, which identified tissue samples from seven cats between 1997 and 2002 with a history of orbital mass effect and pathology characterized by fibrous tissue proliferation. PROCEDURE: Information was obtained from medical records for affected cats, including age, sex, clinical signs, management, and outcome, with histopathology re-examined. RESULTS: Six of seven cats presented with unilateral orbital involvement that progressed to bilateral orbital disease despite treatment. Onset was insidious, evolving over weeks to months and was associated with fixation of orbital structures. Owners of six of the cats opted for euthanasia because of disease progression and pain. Histopathology of affected orbital tissue included extensive fibrosis with encapsulation of normal tissues without characteristics of neoplasia. CONCLUSIONS: Clinical findings and histopathology of globes and orbital tissues in cats bore many similarities to idiopathic sclerosing orbital pseudotumor in humans. In cats, the prognosis for the globe appears to be poor but an elucidation of the pathogenesis and earlier diagnosis coupled with more aggressive treatment modalities as indicated in humans may be beneficial.
Assuntos
Doenças do Gato/patologia , Eutanásia Animal , Doenças Orbitárias/veterinária , Pseudotumor Orbitário/veterinária , Animais , Antibacterianos/uso terapêutico , Doenças do Gato/tratamento farmacológico , Gatos , Progressão da Doença , Imuno-Histoquímica/veterinária , Doenças Orbitárias/tratamento farmacológico , Doenças Orbitárias/patologia , Pseudotumor Orbitário/tratamento farmacológico , Pseudotumor Orbitário/patologia , Prednisona/uso terapêutico , Estudos Retrospectivos , Tomografia Computadorizada por Raios XRESUMO
A leiomyoma of the iris is described in an 11-year-old Yorkshire Terrier. This is a rare primary intraocular tumor in dogs and we describe the clinical presentation, gross findings and histopathologic characteristics of this tumor. The diagnosis was made on the basis of light microscopy and immunohistochemical staining using antidesmin antibodies, which is specific for myogenic tissues. An unusual feature of the tumor was the presence of myxoid change. To our knowledge myxoid change has not been previously described in a primary intraocular leiomyoma.