Detalhe da pesquisa
1.
MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer.
Br J Cancer
; 128(11): 1991-1999, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991255
2.
Phase II proof-of-concept study of atorvastatin in castration-resistant prostate cancer.
BJU Int
; 131(2): 236-243, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35844167
3.
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer.
Proc Natl Acad Sci U S A
; 113(29): 8290-5, 2016 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27357679
4.
Clustering of Toxoplasma gondii Infections Within Families of Congenitally Infected Infants.
Clin Infect Dis
; 61(12): 1815-24, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26405150
5.
Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections.
Proc Natl Acad Sci U S A
; 109(35): 14182-7, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891343
6.
ALOX12 in human toxoplasmosis.
Infect Immun
; 82(7): 2670-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24686056
7.
Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo.
Antimicrob Agents Chemother
; 58(3): 1789-92, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366743
8.
Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.
Bioorg Med Chem Lett
; 23(7): 2035-43, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23453069
9.
Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.
Infect Immun
; 80(12): 4298-308, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23027530
10.
Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009).
Clin Infect Dis
; 54(11): 1595-605, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22499837
11.
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
Antimicrob Agents Chemother
; 56(5): 2666-82, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22354304
12.
P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages.
J Immunol
; 184(12): 7040-6, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20488797
13.
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
Cancer Res
; 82(14): 2565-2575, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675421
14.
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.
EMBO Mol Med
; 14(3): e14764, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014179
15.
NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells.
Infect Immun
; 79(2): 756-66, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21098108
16.
Unrecognized ingestion of Toxoplasma gondii oocysts leads to congenital toxoplasmosis and causes epidemics in North America.
Clin Infect Dis
; 53(11): 1081-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22021924
17.
Rapid discovery of inhibitors of Toxoplasma gondii using hybrid structure-based computational approach.
J Comput Aided Mol Des
; 25(5): 403-11, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21359560
18.
PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer.
Oncogene
; 40(13): 2355-2366, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33654198
19.
18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy.
EJNMMI Res
; 10(1): 143, 2020 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33237350
20.
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.
Nat Commun
; 11(1): 2508, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32427840