Detalhe da pesquisa
1.
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.
Mol Cell
; 52(6): 769-82, 2013 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24268577
2.
Rev-erbα and Rev-erbß coordinately protect the circadian clock and normal metabolic function.
Genes Dev
; 26(7): 657-67, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474260
3.
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
Nature
; 504(7478): 153-7, 2013 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24185009
4.
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.
Genes Dev
; 25(23): 2480-8, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22156208
5.
Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ.
Proc Natl Acad Sci U S A
; 110(46): 18656-61, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24167256
6.
Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome.
Proc Natl Acad Sci U S A
; 109(35): 14140-5, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891325
7.
Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.
Nat Med
; 13(6): 730-5, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17515897
8.
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology.
Nature
; 456(7224): 997-1000, 2008 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19037247
9.
Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.
Blood
; 117(9): 2681-90, 2011 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21205929
10.
Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract.
Circ Res
; 109(11): 1240-9, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21959220
11.
HDAC3 is a critical negative regulator of long-term memory formation.
J Neurosci
; 31(2): 764-74, 2011 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228185
12.
Diet-induced lethality due to deletion of the Hdac3 gene in heart and skeletal muscle.
J Biol Chem
; 286(38): 33301-9, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21808063
13.
Retinol saturase promotes adipogenesis and is downregulated in obesity.
Proc Natl Acad Sci U S A
; 106(4): 1105-10, 2009 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19139408
14.
Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond.
Trends Endocrinol Metab
; 29(8): 560-570, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866502
15.
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
Nat Med
; 23(10): 1150-1157, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846097
16.
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.
J Clin Invest
; 127(4): 1451-1462, 2017 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28240605
17.
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
EMBO Mol Med
; 6(9): 1124-32, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25007801
18.
The orphan nuclear receptors at their 25-year reunion.
J Mol Endocrinol
; 51(3): T115-40, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24096517
19.
A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods.
Mol Endocrinol
; 27(1): 127-34, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23192980
20.
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.
Science
; 331(6022): 1315-9, 2011 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393543