Pesquisa | BVS Violência e Saúde

1.

Chromothriptic cure of WHIM syndrome.

McDermott, David H; Gao, Ji-Liang; Liu, Qian; Siwicki, Marie; Martens, Craig; Jacobs, Paejonette; Velez, Daniel; Yim, Erin; Bryke, Christine R; Hsu, Nancy; Dai, Zunyan; Marquesen, Martha M; Stregevsky, Elina; Kwatemaa, Nana; Theobald, Narda; Long Priel, Debra A; Pittaluga, Stefania; Raffeld, Mark A; Calvo, Katherine R; Maric, Irina; Desmond, Ronan; Holmes, Kevin L; Kuhns, Douglas B; Balabanian, Karl; Bachelerie, Françoise; Porcella, Stephen F; Malech, Harry L; Murphy, Philip M.

Cell ; 160(4): 686-699, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25662009

2.

CRISPR/Cas9-mediated Cxcr4 disease allele inactivation for gene therapy in a mouse model of WHIM syndrome.

Gao, Ji-Liang; Owusu-Ansah, Albert; Yang, Alexander; Yim, Erin; McDermott, David H; Jacobs, Paejonette; Majumdar, Shamik; Choi, Uimook; Sweeney, Colin L; Malech, Harry L; Murphy, Philip M.

Blood ; 142(1): 23-32, 2023 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-36928087

3.

Ulrich Siebenlist (1951-2020).

Murphy, Philip M; Lenardo, Michael J.

Immunity ; 54(3): 391-392, 2021 Mar 09.

Artigo em Inglês | MEDLINE | ID: mdl-33691124

4.

Severe CD8+ T Lymphopenia in WHIM Syndrome Caused by Selective Sequestration in Primary Immune Organs.

Majumdar, Shamik; Pontejo, Sergio M; Jaiswal, Hemant; Gao, Ji-Liang; Salancy, Abigail; Stassenko, Elizabeth; Yamane, Hidehiro; McDermott, David H; Balabanian, Karl; Bachelerie, Françoise; Murphy, Philip M.

J Immunol ; 210(12): 1913-1924, 2023 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-37133343

5.

Perturbations of the T-cell receptor repertoire in response to SARS-CoV-2 in immunocompetent and immunocompromised individuals.

Delmonte, Ottavia M; Oguz, Cihan; Dobbs, Kerry; Myint-Hpu, Katherine; Palterer, Boaz; Abers, Michael S; Draper, Deborah; Truong, Meng; Kaplan, Ian M; Gittelman, Rachel M; Zhang, Yu; Rosen, Lindsey B; Snow, Andrew L; Dalgard, Clifton L; Burbelo, Peter D; Imberti, Luisa; Sottini, Alessandra; Quiros-Roldan, Eugenia; Castelli, Francesco; Rossi, Camillo; Brugnoni, Duilio; Biondi, Andrea; Bettini, Laura Rachele; D'Angio, Mariella; Bonfanti, Paolo; Anderson, Megan V; Saracino, Annalisa; Chironna, Maria; Di Stefano, Mariantonietta; Fiore, Jose Ramon; Santantonio, Teresa; Castagnoli, Riccardo; Marseglia, Gian Luigi; Magliocco, Mary; Bosticardo, Marita; Pala, Francesca; Shaw, Elana; Matthews, Helen; Weber, Sarah E; Xirasagar, Sandhya; Barnett, Jason; Oler, Andrew J; Dimitrova, Dimana; Bergerson, Jenna R E; McDermott, David H; Rao, V Koneti; Murphy, Philip M; Holland, Steven M; Lisco, Andrea; Su, Helen C.

J Allergy Clin Immunol ; 153(6): 1655-1667, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38154666

6.

NF kappa B regulator Bcl3 controls development and function of classical dendritic cells required for resistance to Toxoplasma gondii.

Guha, June; Kang, Byunghyun; Claudio, Estefania; Redekar, Neelam R; Wang, Hongshan; Kelsall, Brian L; Siebenlist, Ulrich; Murphy, Philip M.

PLoS Pathog ; 18(11): e1010502, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36318581

7.

Protean Regulation of Leukocyte Function by Nuclear Lamins.

Walling, Brandon L; Murphy, Philip M.

Trends Immunol ; 42(4): 323-335, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33653660

8.

Chemokines act as phosphatidylserine-bound "find-me" signals in apoptotic cell clearance.

Pontejo, Sergio M; Murphy, Philip M.

PLoS Biol ; 19(5): e3001259, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34038417

9.

Periodontal disease in patients with WHIM syndrome.

Brenchley, Laurie; McDermott, David H; Gardner, Pamela J; Silva, Lakmali M; Gao, Ji-Liang; Cho, Elena; Velez, Daniel; Moutsopoulos, Niki M; Murphy, Philip M; Fraser, David.

J Clin Periodontol ; 51(4): 464-473, 2024 04.

Artigo em Inglês | MEDLINE | ID: mdl-38185798

10.

The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8+ T cells during viral infection.

Jaiswal, Hemant; Ciucci, Thomas; Wang, Hongshan; Tang, Wanhu; Claudio, Estefania; Murphy, Philip M; Bosselut, Rémy; Siebenlist, Ulrich.

PLoS Pathog ; 17(1): e1009249, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33508001

11.

Hematologic disorder-associated Cxcr4 gain-of-function mutation leads to uncontrolled extrafollicular immune response.

Alouche, Nagham; Bonaud, Amélie; Rondeau, Vincent; Hussein-Agha, Rim; Nguyen, Julie; Bisio, Valeria; Khamyath, Mélanie; Crickx, Etienne; Setterblad, Niclas; Dulphy, Nicolas; Mahevas, Matthieu; McDermott, David H; Murphy, Philip M; Balabanian, Karl; Espéli, Marion.

Blood ; 137(22): 3050-3063, 2021 06 03.

Artigo em Inglês | MEDLINE | ID: mdl-33512437

12.

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation.

Delmonte, Ottavia M; Bergerson, Jenna R E; Kawai, Tomoki; Kuehn, Hye Sun; McDermott, David H; Cortese, Irene; Zimmermann, Michael T; Dobbs, A Kerry; Bosticardo, Marita; Fink, Danielle; Majumdar, Shamik; Palterer, Boaz; Pala, Francesca; Dsouza, Nikita R; Pouzolles, Marie; Taylor, Naomi; Calvo, Katherine R; Daley, Stephen R; Velez, Daniel; Agharahimi, Anahita; Myint-Hpu, Katherine; Dropulic, Lesia K; Lyons, Jonathan J; Holland, Steven M; Freeman, Alexandra F; Ghosh, Rajarshi; Similuk, Morgan B; Niemela, Julie E; Stoddard, Jennifer; Kuhns, Douglas B; Urrutia, Raul; Rosenzweig, Sergio D; Walkiewicz, Magdalena A; Murphy, Philip M; Notarangelo, Luigi D.

Blood ; 138(12): 1019-1033, 2021 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-33876203

13.

WHIM syndrome: Immunopathogenesis, treatment and cure strategies.

McDermott, David H; Murphy, Philip M.

Immunol Rev ; 287(1): 91-102, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30565238

14.

Alterations in the spatiotemporal expression of the chemokine receptor CXCR4 in endothelial cells cause failure of hierarchical vascular branching.

Li, Wenling; Liu, Chengyu; Burns, Nathan; Hayashi, Jeffery; Yoshida, Atsufumi; Sajja, Aparna; González-Hernández, Sara; Gao, Ji-Liang; Murphy, Philip M; Kubota, Yoshiaki; Zou, Yong-Rui; Nagasawa, Takashi; Mukouyama, Yoh-Suke.

Dev Biol ; 477: 70-84, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34015362

15.

Structural and functional analysis of Ccr1l1, a Rodentia-restricted eosinophil-selective chemokine receptor homologue.

Kline, Jaclyn M; Heusinkveld, Lauren E; Taranto, Eleanor; Martin, Clare B; Tomasi, Alessandra G; Hsu, Isabel J; Cho, Kyoungin; Khillan, Jaspal S; Murphy, Philip M; Pontejo, Sergio M.

J Biol Chem ; 296: 100373, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33548230

16.

Plerixafor for the Treatment of WHIM Syndrome.

McDermott, David H; Pastrana, Diana V; Calvo, Katherine R; Pittaluga, Stefania; Velez, Daniel; Cho, Elena; Liu, Qian; Trout, Hugh H; Neves, João F; Gardner, Pamela J; Bianchi, David A; Blair, Elizabeth A; Landon, Emily M; Silva, Susana L; Buck, Christopher B; Murphy, Philip M.

N Engl J Med ; 380(2): 163-170, 2019 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-30625055

17.

Leukocyte chemotactic receptor Fpr1 protects against aging-related posterior subcapsular cataract formation.

Gao, Ji-Liang; Weaver, Joseph D; Tuo, Jingsheng; Wang, Long Q; Siwicki, Marie; Despres, Daryl; Lizak, Martin; Schneider, Erich H; Kovacs, William; Maminishkis, Arvydas; Chen, Keqiang; Yoshimura, Teizo; Ming Wang, Ji; Chao Chan, Chi; Murphy, Philip M.

FASEB J ; 35(2): e21315, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33538366

18.

A Critical Role of Formyl Peptide Receptors in Host Defense against Escherichia coli.

Zhang, Meihua; Gao, Ji-Liang; Chen, Keqiang; Yoshimura, Teizo; Liang, Weiwei; Gong, Wanghua; Li, Xiaoqing; Huang, Jiaqiang; McDermott, David H; Murphy, Philip M; Wang, Xietong; Wang, Ji Ming.

J Immunol ; 204(9): 2464-2473, 2020 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-32221037

19.

TREC Screening for WHIM Syndrome.

Evans, Martin Oman; Petersen, Maureen M; Khojah, Amer; Jyonouchi, Soma C; Edwardson, George S; Khan, Yasmin West; Connelly, James Albert; Morris, David; Majumdar, Shamik; McDermott, David H; Walter, Jolan E; Murphy, Philip M.

J Clin Immunol ; 41(3): 621-628, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33415666

20.

Bcl-3 suppresses differentiation of RORÎ³t⁺ regulatory T cells.

Tang, Wanhu; Saret, Sun; Tian, Ruxiao; Wang, Hongshan; Claudio, Estefania; Murphy, Philip M; Siebenlist, Ulrich.

Immunol Cell Biol ; 99(6): 586-595, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33525048

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