RESUMO
On 2 November 1999, one of the main hospital façades adjoining cardiovascular surgery collapsed in a 900-bed teaching hospital in Santander, Spain. The purpose of this study was to determine whether the accident affected the safety of patients by increasing the risk for nosocomial and surgical site infections (SSI). Measures for the prevention of nosocomial infections were immediately reinforced. A total of 217 consecutive patients were operated on before 2 November 1999, with another 296 after this date. Patients in both study periods showed similar severity of illness, complexity of surgical procedure and length of hospital stay. The overall rate of nosocomial infection before and after the accident was 28.1% and 24.7%, respectively (P=0.381). The rates of respiratory infection, urinary infection and bacteraemia were also similar. A statistically significant reduction in the SSI rate in the second period was observed (14.8% vs 4.4%, P=0.008). The collapse of the façade was not associated with any increase in nosocomial infection rates, but there was a significant reduction of SSI rates in relation to intensive infection control measures implemented after the collapse.
Assuntos
Infecção Hospitalar/epidemiologia , Infecção da Ferida Cirúrgica/epidemiologia , Cirurgia Torácica , Idoso , Bacteriemia/epidemiologia , Feminino , Hospitais de Ensino , Humanos , Tempo de Internação , Masculino , Prevalência , Infecções Respiratórias/epidemiologia , Índice de Gravidade de Doença , Espanha , Infecções Urinárias/epidemiologiaRESUMO
Consumers of adulterated drugs may present with talc-induced interstitial lung disease. A transbronchial biopsy specimen showing granulomas with intracellular talc crystals is necessary to confirm this diagnosis. In patients infected with HIV, such a condition can be indistinguishable at first glance from opportunistic infections or other pulmonary diseases. A case is presented of a seropositive patient whose chest radiographs showed a diffuse interstitial pattern.
Assuntos
Granuloma de Corpo Estranho/etiologia , Granuloma do Sistema Respiratório/etiologia , Infecções por HIV/complicações , Doenças Pulmonares Intersticiais/etiologia , Talco/efeitos adversos , Adulto , Diagnóstico Diferencial , Evolução Fatal , Granuloma de Corpo Estranho/diagnóstico por imagem , Granuloma de Corpo Estranho/patologia , Granuloma do Sistema Respiratório/diagnóstico por imagem , Granuloma do Sistema Respiratório/patologia , Humanos , Doenças Pulmonares Intersticiais/diagnóstico por imagem , Doenças Pulmonares Intersticiais/patologia , Masculino , RadiografiaAssuntos
Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/microbiologia , Vértebras Lombares/microbiologia , Neoplasias Pulmonares/diagnóstico , Osteomielite/diagnóstico , Osteomielite/microbiologia , Neoplasias da Bexiga Urinária/diagnóstico , Adenocarcinoma/complicações , Adenocarcinoma/diagnóstico , Anti-Infecciosos/uso terapêutico , Carcinoma de Células de Transição/complicações , Carcinoma de Células de Transição/diagnóstico , Infecções Comunitárias Adquiridas/diagnóstico , Infecções Comunitárias Adquiridas/microbiologia , Infecções por Corynebacterium/complicações , Infecções por Corynebacterium/tratamento farmacológico , Diagnóstico Diferencial , Humanos , Dor Lombar/microbiologia , Neoplasias Pulmonares/complicações , Masculino , Pessoa de Meia-Idade , Osteomielite/complicações , Osteomielite/tratamento farmacológico , Resultado do Tratamento , Neoplasias da Bexiga Urinária/complicaçõesRESUMO
Cardiomyopathies are a clinically and genetically heterogeneous group of cardiac diseases in which the myocardium is primarily involved. Mitochondrial DNA point mutations have been identified in a broad spectrum of mitochondrial disorders, which are associated with neurological diseases. However, they also have been reported in patients with cardiomyopathy, either alone or as part of a multisystem disorder. A patient who presented with severe heart failure and was diagnosed as having a mitochondrial A3243G mutation is described.