Pesquisa | BVS Violência e Saúde

1.

Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in mice.

Bristol, Jillian A; Nelson, Scott E; Ohashi, Makoto; Casco, Alejandro; Hayes, Mitchell; Ranheim, Erik A; Pawelski, Abigail S; Singh, Deo R; Hodson, Daniel J; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 20(4): e1012132, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38620028

2.

Epstein-Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ.

Singh, Deo R; Nelson, Scott E; Pawelski, Abigail S; Kansra, Alisha S; Fogarty, Stuart A; Bristol, Jillian A; Ohashi, Makoto; Johannsen, Eric C; Kenney, Shannon C.

Proc Natl Acad Sci U S A ; 120(20): e2219755120, 2023 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-37155846

3.

Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.

Bristol, Jillian A; Brand, Joshua; Ohashi, Makoto; Eichelberg, Mark R; Casco, Alejandro; Nelson, Scott E; Hayes, Mitchell; Romero-Masters, James C; Baiu, Dana C; Gumperz, Jenny E; Johannsen, Eric C; Dinh, Huy Q; Kenney, Shannon C.

PLoS Pathog ; 18(4): e1010453, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35472072

4.

Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes.

Singh, Deo R; Nelson, Scott E; Pawelski, Abigail S; Cantres-Velez, Juan A; Kansra, Alisha S; Pauly, Nicholas P; Bristol, Jillian A; Hayes, Mitchell; Ohashi, Makoto; Casco, Alejandro; Lee, Denis; Fogarty, Stuart A; Lambert, Paul F; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 18(10): e1010868, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36190982

5.

Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression.

Beauvais, DeannaLee M; Nelson, Scott E; Adams, Kristin M; Stueven, Noah A; Jung, Oisun; Rapraeger, Alan C.

J Biol Chem ; 298(6): 102029, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35569509

6.

Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells.

Van Sciver, Nicholas; Ohashi, Makoto; Pauly, Nicholas P; Bristol, Jillian A; Nelson, Scott E; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 17(8): e1009783, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34339458

7.

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.

Romero-Masters, James C; Huebner, Shane M; Ohashi, Makoto; Bristol, Jillian A; Benner, Bayleigh E; Barlow, Elizabeth A; Turk, Gail L; Nelson, Scott E; Baiu, Dana C; Van Sciver, Nicholas; Ranheim, Erik A; Gumperz, Jenny; Sherer, Nathan M; Farrell, Paul J; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 16(2): e1008365, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-32059024

8.

EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice.

Li, Chunrong; Romero-Masters, James C; Huebner, Shane; Ohashi, Makoto; Hayes, Mitchell; Bristol, Jillian A; Nelson, Scott E; Eichelberg, Mark R; Van Sciver, Nicholas; Ranheim, Erik A; Scott, Rona S; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 16(6): e1008590, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32542010

9.

An EBNA3A-Mutated Epstein-Barr Virus Retains the Capacity for Lymphomagenesis in a Cord Blood-Humanized Mouse Model.

Romero-Masters, James C; Ohashi, Makoto; Djavadian, Reza; Eichelberg, Mark R; Hayes, Mitchell; Zumwalde, Nicholas A; Bristol, Jillian A; Nelson, Scott E; Ma, Shidong; Ranheim, Erik A; Gumperz, Jenny E; Johannsen, Eric C; Kenney, Shannon C.

J Virol ; 94(10)2020 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-32132242

10.

Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair.

Mohd, Azizah B; Palama, Brett; Nelson, Scott E; Tomer, Guy; Nguyen, Megan; Huo, Xin; Buermeyer, Andrew B.

DNA Repair (Amst) ; 5(3): 347-61, 2006 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-16338176

11.

Addition of insulin to oral therapy in patients with type 2 diabetes.

Nelson, Scott E; Palumbo, Pasquale J.

Am J Med Sci ; 331(5): 257-63, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16702795

12.

Changes in the expression of the NR2B subunit during aging in macaque monkeys.

Bai, Ling; Hof, Patrick R; Standaert, David G; Xing, Yiding; Nelson, Scott E; Young, Anne B; Magnusson, Kathy R.

Neurobiol Aging ; 25(2): 201-8, 2004 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-14749138

13.

The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein.

Ellsworth, Buffy S; Burns, Ann T; Escudero, Kenneth W; Duval, Dawn L; Nelson, Scott E; Clay, Colin M.

Mol Cell Endocrinol ; 206(1-2): 93-111, 2003 Aug 29.

Artigo em Inglês | MEDLINE | ID: mdl-12943993

14.

Homer1a and 1bc levels in the rat somatosensory cortex vary with the time of day and sleep loss.

Nelson, Scott E; Duricka, Deborah L; Campbell, Kenneth; Churchill, Lynn; Krueger, James M.

Neurosci Lett ; 367(1): 105-8, 2004 Aug 26.

Artigo em Inglês | MEDLINE | ID: mdl-15308308

15.

Management of patients with type 2 diabetes.

Nelson, Scott E.

Curr Med Res Opin ; 27(10): 1931-47, 2011 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-21867459

16.

Detemir as a once-daily basal insulin in type 2 diabetes.

Nelson, Scott E.

Clin Pharmacol ; 3: 27-37, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-22287854

17.

Assessing the controversies of insulin therapy in patients with type 2 diabetes mellitus.

Kuritzky, Louis; Nelson, Scott E.

J Fam Pract ; 54(6): S3-6, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16021782

18.

Beneficial effects of insulin on endothelial function, inflammation, and atherogenesis and their implications.

Kuritzky, Louis; Nelson, Scott E.

J Fam Pract ; 54(6): S7-9, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16021783

19.

Insulin therapy in primary care: practical issues for clinicians.

Kuritzky, Louis; Nelson, Scott E.

J Fam Pract ; 54(6): S10-11, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16021784

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Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in mice.

Epstein-Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ.

Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.

Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes.

Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression.

Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells.

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.

EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice.

An EBNA3A-Mutated Epstein-Barr Virus Retains the Capacity for Lymphomagenesis in a Cord Blood-Humanized Mouse Model.

Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair.

Addition of insulin to oral therapy in patients with type 2 diabetes.

Changes in the expression of the NR2B subunit during aging in macaque monkeys.

The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein.

Homer1a and 1bc levels in the rat somatosensory cortex vary with the time of day and sleep loss.

Management of patients with type 2 diabetes.

Detemir as a once-daily basal insulin in type 2 diabetes.

Assessing the controversies of insulin therapy in patients with type 2 diabetes mellitus.

Beneficial effects of insulin on endothelial function, inflammation, and atherogenesis and their implications.

Insulin therapy in primary care: practical issues for clinicians.