Detalhe da pesquisa
1.
Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.
Hum Mol Genet
; 24(21): 6080-92, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26246497
2.
Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.
Hum Mol Genet
; 20(1): 165-75, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940146
3.
Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.
Proc Natl Acad Sci U S A
; 107(19): 8683-8, 2010 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20421483
4.
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.
Hum Mol Genet
; 19(8): 1387-98, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080939
5.
Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours.
Clin Endocrinol (Oxf)
; 77(2): 195-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22335482
6.
Role of nonselective cation channels in spontaneous and protein kinase A-stimulated calcium signaling in pituitary cells.
Am J Physiol Endocrinol Metab
; 301(2): E370-9, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21586701
7.
Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation.
Mol Cell Endocrinol
; 522: 111117, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33338547
8.
Investigation of a patient with a partial trisomy 16q including the fat mass and obesity associated gene (FTO): fine mapping and FTO gene expression study.
Am J Med Genet A
; 152A(3): 630-7, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20186806
9.
Deformation and fracture of crystalline tungsten and fabrication of composite STM probes.
Ultramicroscopy
; 218: 113083, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32739752
10.
Large deletions of the PRKAR1A gene in Carney complex.
Clin Cancer Res
; 14(2): 388-95, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18223213
11.
In vitro functional studies of naturally occurring pathogenic PRKAR1A mutations that are not subject to nonsense mRNA decay.
Hum Mutat
; 29(5): 633-9, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18241045
12.
An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of overexpression of the wild-type Allele and other protein kinase A subunits.
J Clin Endocrinol Metab
; 93(2): 565-71, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18056771
13.
Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine.
J Clin Endocrinol Metab
; 93(3): 1020-9, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18073299
14.
A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.
Eur J Hum Genet
; 16(10): 1245-53, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18431404
15.
Autoantibody cancer biomarker: extracellular protein kinase A.
Cancer Res
; 66(18): 8971-4, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16982736
16.
Acute vs chronic exposure to high fat diet leads to distinct regulation of PKA.
J Mol Endocrinol
; 59(1): 1-12, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420713
17.
Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects.
Mol Cell Endocrinol
; 439: 165-174, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27498419
18.
CpG immunomer DNA enhances antisense protein kinase A RIalpha inhibition of multidrug-resistant colon carcinoma growth in nude mice: molecular basis for combinatorial therapy.
Clin Cancer Res
; 11(16): 5950-5, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16115938
19.
Studies of mice with cyclic AMP-dependent protein kinase (PKA) defects reveal the critical role of PKA's catalytic subunits in anxiety.
Behav Brain Res
; 307: 1-10, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26992826
20.
Bilateral Adrenal Hyperplasia as a Possible Mechanism for Hyperandrogenism in Women With Polycystic Ovary Syndrome.
J Clin Endocrinol Metab
; 101(9): 3353-60, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27336356