Detalhe da pesquisa
1.
Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.
Bioorg Med Chem
; 34: 116034, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548803
2.
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Bioorg Med Chem Lett
; 29(17): 2503-2510, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31327531
3.
Enantioselective total synthesis of (+)-ophiobolinâ A.
Chemistry
; 19(17): 5476-86, 2013 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447120
4.
Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes.
Methods Enzymol
; 638: 69-87, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32416922
5.
Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety.
J Med Chem
; 63(18): 10352-10379, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32900194
6.
Discovery of 3,5-Diphenyl-4-methyl-1,3-oxazolidin-2-ones as Novel, Potent, and Orally Available Δ-5 Desaturase (D5D) Inhibitors.
J Med Chem
; 60(21): 8963-8981, 2017 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023121
7.
Synthetic studies on (+)-ophiobolin A: asymmetric synthesis of the spirocyclic CD-ring moiety.
Org Lett
; 8(10): 2039-42, 2006 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16671776
8.
Convergent total synthesis of (+)-ophiobolin A.
Angew Chem Int Ed Engl
; 50(40): 9452-5, 2011 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21915975