[Senile macula and cerebral functions]. / Macula sénile et fonctions cérébrales.

Because of similarities in the physiology and histology of the intraocular and the cerebral circulations, a study of cerebral disorders in patients with senile macular choroidal degeneration (S.M.C.D.) was undertaken. Of 26 cases of S.M.C.D. with sufficient follow-up, 7 showed signs of cerebral disfunction. Types of problems most often found were inordinate disturbances of short-term memory, judgement, and social behavior. It appears that S.M.C.D. tends more to be associated with mental involution than with sensory-motor deficits. Various methods of investigating the cerebro-vascular circulation can be helpful in discussing causes of mental involution, including doppler ultrasound, echotomography Xemon 133 inhalation, positron emission tomography, C.T. scanning, and nuclear magnetic resonance scanning. The physiopathology may involve relative cerebral ischemia, modification of neurotransmitters, and free radical formation, as well as immunologic factors. Specific treatment may one day become reality.

[Intraocular penetration of collyria]. / De la pénétration intraoculaire des collyres.

UNLABELLED: Some ophthalmic solutions activity is localized at the eye's surface: they are used to manage conjunctivitis and keratitis. Some others must penetrate the eye. They are carried through the cornea. There are many factors allowing the penetration into the cornea. These factors will be studied in this paper. Bio-physical and bio-chemical actions are both numerous and complex. IN CONCLUSION: the different corneal tissues have a selective solubility to ophthalmic solution components.

[Malignant lymphoplasmocytic lymphoma of the orbit and conjunctiva (author's transl)]. / Le lymphome malin lymphoplasmocytaire de l'orbite et de la conjonctive.

New functional classifications of malignant lymphomas have demonstrated the relative frequency of malignant lymphoplasmocytic lymphoma of the orbit. The tumors, which show the particular characteristic of secreting monoclonal immunoglobulins, and which may follow a Sjögren's syndrome or a pseudolymphoma, could represent a localized form of Waldenström's disease. They have a relatively favorable prognosis, however, if recognized at a sufficiently early stage.

[Orbital immunoblastosarcoma (author's transl)]. / Immunoblastosarcome de l'orbite.

The new classifications adopted for lymphoid tumors now include a particular type of proliferative process: immunoblastosarcoma. This tumor is not a rare occurrence in the orbit, as shown by the two cases reported, and possesses sufficiently specific clinical and histologicas characteristics to justify its appearance in a separate class. The cytological and histological characteristics of the immunoblasts from which it develops are described. Tumors of this type were previously mostly included in the group of reticulosarcomas, now become obsolete because of poorly defined characteristics of the reticular cell. The prognosis is poor in spite of the chemotherapeutic and radiotherapeutic treatments proposed.