1.
Chemistry
; 28(8): e202104421, 2022 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34984747
RESUMO
Aqueous self-assembly of short peptides has attracted growing attention for the construction of supramolecular materials for various bioapplications. Herein, we describe how the thermolysin-assisted biocatalytic construction of a dipeptide hydrazide from an N-protected amino acid and an amino acid hydrazide leads to the formation of thermally stable supramolecular hydrogels. In addition, we demonstrate the post-assembly modification of the supramolecular architectures constructed inâ situ tethering hydrazide groups as a chemical handle by means of fluorescence imaging.