Detalhe da pesquisa
1.
Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors.
Molecules
; 25(10)2020 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414020
2.
Fluorescence Polarization-Based Competition Assays to Evaluate Histone Deacetylase 6 Inhibitors.
Methods Mol Biol
; 2589: 481-492, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36255644
3.
Phenotypic Screening of Histone Deacetylase (HDAC) Inhibitors against Schistosoma mansoni.
ChemMedChem
; 17(18): e202100622, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35983937
4.
Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma.
J Med Chem
; 65(4): 3193-3217, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35119267
5.
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
EMBO Mol Med
; 14(12): e15200, 2022 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36341492
6.
Unique Molecular Interaction with the Histone Deacetylase 6 Catalytic Tunnel: Crystallographic and Biological Characterization of a Model Chemotype.
J Med Chem
; 64(5): 2691-2704, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576627
7.
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.
J Med Chem
; 64(12): 8486-8509, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101461
8.
Optimization of a high-throughput fluorescence polarization assay for STAT5B DNA binding domain-targeting inhibitors.
J Pharm Biomed Anal
; 184: 113182, 2020 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32113119
9.
Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 Targeting.
J Med Chem
; 63(15): 8634-8648, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672458
10.
PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia.
Eur J Med Chem
; 201: 112411, 2020 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32615502
11.
Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia.
ACS Med Chem Lett
; 11(1): 56-64, 2020 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31938464