Detalhe da pesquisa
1.
Synthesis, characterization, antioxidant and antiparasitic activities new naphthyl-thiazole derivatives.
Exp Parasitol
; 248: 108498, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907541
2.
COVID-19 therapy: What weapons do we bring into battle?
Bioorg Med Chem
; 28(23): 115757, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32992245
3.
Thiazolidinedione and thiazole derivatives potentiate norfloxacin activity against NorA efflux pump over expression in Staphylococcus aureus 1199B strains.
Bioorg Med Chem
; 27(17): 3797-3804, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320212
4.
Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
Bioorg Med Chem
; 26(22): 5911-5921, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420325
5.
Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Bioorg Med Chem
; 26(20): 5388-5396, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293795
6.
Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine.
Bioorg Med Chem
; 25(13): 3259-3277, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495384
7.
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety.
Int J Biol Macromol
; 254(Pt 3): 127651, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37949265
8.
Interaction study with DNA/HSA, anti-topoisomerase IIα, cytotoxicity and in vitro antiproliferative evaluations and molecular docking of indole-thiosemicarbazone compounds.
Int J Biol Macromol
; 234: 123606, 2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36773880
9.
Neurolocomotor Behavior and Oxidative Stress Markers of Thiazole and Thiazolidinedione Derivatives against Nauphoeta cinerea.
Antioxidants (Basel)
; 11(2)2022 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35204302
10.
Synthesis, in vitro schistosomicidal activity and ultrastructural alterations caused by thiosemicarbazones and thiazolidinones against juvenile and adult Schistosoma mansoni worms (Sambon, 1907).
Mol Biochem Parasitol
; 252: 111520, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122704
11.
Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders.
Int J Biol Macromol
; 170: 622-635, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359805
12.
New Oxazolidines Inhibit the Secretion of IFN-γ and IL-17 by PBMCS from Moderate to Severe Asthmatic Patients.
Med Chem
; 17(3): 289-297, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32914717
13.
Novel indol-3-yl-thiosemicarbazone derivatives: Obtaining, evaluation of in vitro leishmanicidal activity and ultrastructural studies.
Chem Biol Interact
; 315: 108899, 2020 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31738906
14.
Thiophene-thiosemicarbazone derivative (L10) exerts antifungal activity mediated by oxidative stress and apoptosis in C. albicans.
Chem Biol Interact
; 320: 109028, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32119865
15.
Topoisomerase inhibition and albumin interaction studies of acridine-thiosemicarbazone derivatives.
Int J Biol Macromol
; 138: 582-589, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31323270
16.
In vitro activity, ultrastructural studies and in silico pharmacokinetic properties of indol-3-yl-thiosemicarbazones derivatives and analogues against juvenile and adult worms of S. mansoni.
Eur J Pharm Sci
; 138: 104985, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31283945
17.
Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition.
Eur J Med Chem
; 182: 111592, 2019 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31421632
18.
New 1,3-benzodioxole derivatives: Synthesis, evaluation of in vitro schistosomicidal activity and ultrastructural analysis.
Chem Biol Interact
; 283: 20-29, 2018 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366735
19.
New thiophene-acridine compounds: Synthesis, antileishmanial activity, DNA binding, chemometric, and molecular docking studies.
Chem Biol Drug Des
; 91(6): 1141-1155, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415325
20.
DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents?
Biomed Pharmacother
; 96: 1538-1556, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29174576