Detalhe da pesquisa
1.
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Cell
; 184(2): 384-403.e21, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450205
2.
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Mol Cell
; 67(1): 5-18.e19, 2017 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673542
3.
A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation.
J Biol Chem
; 295(6): 1694-1703, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914414
4.
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation.
Nat Chem Biol
; 14(2): 163-170, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29251720
5.
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Nat Chem Biol
; 12(10): 876-84, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27571479
6.
Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors.
Cell Chem Biol
; 28(2): 134-147.e14, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33086052
7.
Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13.
J Med Chem
; 63(13): 6708-6726, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32502343
8.
Development and Characterization of a Wee1 Kinase Degrader.
Cell Chem Biol
; 27(1): 57-65.e9, 2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31735695
9.
Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.
Cell Chem Biol
; 26(6): 792-803.e10, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905681
10.
IRF2 is a master regulator of human keratinocyte stem cell fate.
Nat Commun
; 10(1): 4676, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611556
11.
Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors.
Cell Rep
; 21(2): 467-481, 2017 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29020632
12.
The insulin receptor cellular IRES confers resistance to eIF4A inhibition.
Elife
; 2: e00542, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23878722
13.
Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.
J Mol Signal
; 8(1): 3, 2013 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23531275