Detalhe da pesquisa
1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell
; 184(24): 5886-5901.e22, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822784
2.
The Neutrophil Dynamic Mass Redistribution Assay as a Medium throughput Primary Cell Screening Assay.
J Pharmacol Exp Ther
; 389(1): 19-31, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863490
3.
The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.
Bioorg Med Chem Lett
; 20(2): 759-62, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005096
4.
Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses.
J Med Chem
; 59(3): 1003-20, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26751273
5.
Monoclonal anti-ß1-adrenergic receptor antibodies activate G protein signaling in the absence of ß-arrestin recruitment.
MAbs
; 6(1): 246-61, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24253107
6.
Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate.
ACS Med Chem Lett
; 2(6): 444-9, 2011 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900328
7.
Discovery of a brain-penetrant S1P3-sparing direct agonist of the S1P1 and S1P5 receptors efficacious at low oral dose.
J Med Chem
; 54(19): 6724-33, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21838322