Detalhe da pesquisa
1.
Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif.
J Biol Chem
; 297(4): 101175, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34499924
2.
The Reaction Mechanism of Metallo-ß-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348667
3.
Structural and functional characterization of a cold adapted TPM-domain with ATPase/ADPase activity.
J Struct Biol
; 197(3): 201-209, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27810564
4.
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function.
Proc Natl Acad Sci U S A
; 110(42): 16808-13, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24085846
5.
Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
J Am Chem Soc
; 137(5): 1738-41, 2015 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25629446
6.
Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain.
Proteins
; 82(11): 3062-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25116514
7.
Structural basis for the broad specificity of a new family of amino-acid racemases.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 1): 79-90, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419381
8.
Disruption of allosteric response as an unprecedented mechanism of resistance to antibiotics.
J Am Chem Soc
; 136(28): 9814-7, 2014 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24955778
9.
A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers.
mBio
; 14(2): e0002323, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36786587
10.
Cross-protection and cross-neutralization capacity of ancestral and VOC-matched SARS-CoV-2 adenoviral vector-based vaccines.
NPJ Vaccines
; 8(1): 149, 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794010
11.
Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase.
Biochim Biophys Acta
; 1814(7): 858-63, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515416
12.
A disordered region retains the full protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of the oral vaccine adjuvant U-Omp19.
Comput Struct Biotechnol J
; 20: 5098-5114, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36187929
13.
Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase.
mBio
; 12(2)2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879593
14.
Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats.
J Physiol Biochem
; 77(4): 565-576, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097242
15.
Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.
Sci Adv
; 7(48): eabh1097, 2021 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818032
16.
Preparation and biophysical characterization of recombinant Pseudomonas aeruginosa phosphorylcholine phosphatase.
Protein Expr Purif
; 71(2): 153-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064618
17.
Crystallization and preliminary X-ray diffraction analysis of Pseudomonas aeruginosa phosphorylcholine phosphatase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 66(Pt 8): 957-60, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693680
18.
Transition from octahedral to tetrahedral geometry causes the activation or inhibition by Znf2+ of Pseudomonas aeruginosa phosphorylcholine phosphatase.
Biometals
; 23(2): 307-14, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20135339
19.
Crystal structures of peanut lectin in the presence of synthetic ß-N- and ß-S-galactosides disclose evidence for the recognition of different glycomimetic ligands.
Acta Crystallogr D Struct Biol
; 76(Pt 11): 1080-1091, 2020 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33135679
20.
Development of a hyperimmune equine serum therapy for COVID-19 in Argentina.
Medicina (B Aires)
; 80 Suppl 3: 1-6, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658841