Detalhe da pesquisa
1.
Qualification of impurities based on metabolite data.
Regul Toxicol Pharmacol
; 110: 104524, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734179
2.
Development of hydrolytic stability screening methods for early drug discovery with high differentiation and predictive power.
J Pharm Biomed Anal
; 233: 115478, 2023 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37245329
3.
The Degradation Map Process - A Tool for Obtaining a Lean Stability Strategy in Drug Development.
J Pharm Sci
; 111(7): 1918-1925, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34929157
4.
Characterization and demonstration of drug compound ring-chain tautomer formation and its impacts on quality control.
J Pharm Biomed Anal
; 198: 114020, 2021 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740606
5.
A global view of protein expression in human cells, tissues, and organs.
Mol Syst Biol
; 5: 337, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-20029370
6.
Increased levels of recombinant human proteins with the Escherichia coli strain Rosetta(DE3).
Protein Expr Purif
; 69(2): 159-67, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19733669
7.
A genecentric Human Protein Atlas for expression profiles based on antibodies.
Mol Cell Proteomics
; 7(10): 2019-27, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18669619
8.
A general, robust method for the quality control of intact proteins using LC-ESI-MS.
J Chromatogr B Analyt Technol Biomed Life Sci
; 852(1-2): 188-94, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17267305
9.
High-throughput solubility assay for purified recombinant protein immunogens.
Biochim Biophys Acta
; 1752(1): 6-10, 2005 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-16084133
10.
Size as a parameter for solvent effects on Candida antarctica lipase B enantioselectivity.
Biochim Biophys Acta
; 1594(2): 325-34, 2002 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-11904228
11.
A novel flow cytometry-based method for analysis of expression levels in Escherichia coli, giving information about precipitated and soluble protein.
J Biotechnol
; 119(2): 133-46, 2005 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15996784
12.
Experimental and Quantum Chemical Evaluations of Pyridine Oxidation Under Drug Development Stress Test Conditions.
J Pharm Sci
; 104(12): 4355-4364, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26523412
13.
Substrate entropy in enzyme enantioselectivity: an experimental and molecular modeling study of a lipase.
Protein Sci
; 11(6): 1462-71, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021445
14.
Enhancing the protein production levels in Escherichia coli with a strong promoter.
FEBS J
; 278(5): 729-39, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21205203
15.
Parallel production and verification of protein products using a novel high-throughput screening method.
Biotechnol J
; 6(8): 1018-25, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21681961
16.
Surrogate antigens as targets for proteome-wide binder selection.
N Biotechnol
; 28(4): 302-11, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21232647
17.
Automated sample preparation method for mass spectrometry analysis on recombinant proteins.
J Chromatogr A
; 1216(20): 4457-64, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345368
18.
High-throughput protein production--lessons from scaling up from 10 to 288 recombinant proteins per week.
Biotechnol J
; 4(1): 51-7, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19039781
19.
High-throughput protein purification under denaturating conditions by the use of cation exchange chromatography.
Biotechnol J
; 2(6): 709-16, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17492715
20.
High-throughput protein purification using an automated set-up for high-yield affinity chromatography.
Protein Expr Purif
; 46(2): 173-8, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16483795