Detalhe da pesquisa
1.
Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer.
Nucleic Acids Res
; 50(4): 1829-1848, 2022 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35166828
2.
A Novel Strategy for Regulating mRNA's Degradation via Interfering the AUF1's Binding to mRNA.
Molecules
; 27(10)2022 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35630659
3.
Probes and drugs that interfere with protein translation via targeting to the RNAs or RNA-protein interactions.
Methods
; 167: 124-133, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31185274
4.
Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.
Nucleic Acids Res
; 45(4): 1606-1618, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27923993
5.
Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acidâ»Protein Interaction.
Molecules
; 24(3)2019 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678288
6.
Tracking the Dynamic Folding and Unfolding of RNA G-Quadruplexes in Live Cells.
Angew Chem Int Ed Engl
; 57(17): 4702-4706, 2018 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29453903
7.
Curcusone C induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2.
Biochim Biophys Acta Proteins Proteom
; 1865(11 Pt A): 1372-1382, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28870734
8.
Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2.
Biochim Biophys Acta Gen Subj
; 1861(12): 3246-3256, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28943299
9.
Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule.
Nucleic Acids Res
; 43(14): 6677-91, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26117539
10.
Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe.
J Am Chem Soc
; 138(33): 10382-5, 2016 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27508892
11.
G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression.
Biochim Biophys Acta
; 1840(7): 2222-33, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24631651
12.
Cellular nucleic acid binding protein suppresses tumor cell metastasis and induces tumor cell death by downregulating heterogeneous ribonucleoprotein K in fibrosarcoma cells.
Biochim Biophys Acta
; 1840(7): 2244-52, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24594223
13.
Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives.
Biochim Biophys Acta
; 1840(9): 2970-7, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24931695
14.
Mechanistic studies on the anticancer activity of 2,4-disubstituted quinazoline derivative.
Biochim Biophys Acta
; 1840(10): 3123-30, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25018006
15.
Development of a highly sensitive fluorescent light-up probe for G-quadruplexes.
Analyst
; 140(13): 4616-25, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26027520
16.
Discovery of natural alkaloid bouchardatine as a novel inhibitor of adipogenesis/lipogenesis in 3T3-L1 adipocytes.
Bioorg Med Chem
; 23(15): 4719-4727, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26088335
17.
Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription.
Biochim Biophys Acta
; 1830(10): 4769-77, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23774591
18.
The role of positive charges on G-quadruplex binding small molecules: learning from bisaryldiketene derivatives.
Biochim Biophys Acta
; 1830(11): 5006-13, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23880070
19.
Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation.
Eur J Med Chem
; 271: 116406, 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688064
20.
Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: implications for epigenetic regulation.
Biochem Biophys Res Commun
; 433(4): 368-73, 2013 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23261425