Pesquisa | BVS Violência e Saúde

1.

Constructing human neural circuits in living systems by transplantation.

PaÈca, Sergiu P.

Cell ; 187(1): 8-13, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38181744

2.

Human brain organogenesis: Toward a cellular understanding of development and disease.

Kelley, Kevin W; PaÈca, Sergiu P.

Cell ; 185(1): 42-61, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34774127

3.

Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution.

Trevino, Alexandro E; Müller, Fabian; Andersen, Jimena; Sundaram, Laksshman; Kathiria, Arwa; Shcherbina, Anna; Farh, Kyle; Chang, Howard Y; PaÈca, Anca M; Kundaje, Anshul; PaÈca, Sergiu P; Greenleaf, William J.

Cell ; 184(19): 5053-5069.e23, 2021 09 16.

Artigo em Inglês | MEDLINE | ID: mdl-34390642

4.

Antisense oligonucleotide therapeutic approach for Timothy syndrome.

Chen, Xiaoyu; Birey, Fikri; Li, Min-Yin; Revah, Omer; Levy, Rebecca; Thete, Mayuri Vijay; Reis, Noah; Kaganovsky, Konstantin; Onesto, Massimo; Sakai, Noriaki; Hudacova, Zuzana; Hao, Jin; Meng, Xiangling; Nishino, Seiji; Huguenard, John; PaÈca, Sergiu P.

Nature ; 628(8009): 818-825, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38658687

5.

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment.

Meng, Xiangling; Yao, David; Imaizumi, Kent; Chen, Xiaoyu; Kelley, Kevin W; Reis, Noah; Thete, Mayuri Vijay; Arjun McKinney, Arpana; Kulkarni, Shravanti; Panagiotakos, Georgia; Bassik, Michael C; PaÈca, Sergiu P.

Nature ; 622(7982): 359-366, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37758944

6.

Maturation and circuit integration of transplanted human cortical organoids.

Revah, Omer; Gore, Felicity; Kelley, Kevin W; Andersen, Jimena; Sakai, Noriaki; Chen, Xiaoyu; Li, Min-Yin; Birey, Fikri; Yang, Xiao; Saw, Nay L; Baker, Samuel W; Amin, Neal D; Kulkarni, Shravanti; Mudipalli, Rachana; Cui, Bianxiao; Nishino, Seiji; Grant, Gerald A; Knowles, Juliet K; Shamloo, Mehrdad; Huguenard, John R; Deisseroth, Karl; PaÈca, Sergiu P.

Nature ; 610(7931): 319-326, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36224417

7.

A tissue-like neurotransmitter sensor for the brain and gut.

Li, Jinxing; Liu, Yuxin; Yuan, Lei; Zhang, Baibing; Bishop, Estelle Spear; Wang, Kecheng; Tang, Jing; Zheng, Yu-Qing; Xu, Wenhui; Niu, Simiao; Beker, Levent; Li, Thomas L; Chen, Gan; Diyaolu, Modupeola; Thomas, Anne-Laure; Mottini, Vittorio; Tok, Jeffrey B-H; Dunn, James C Y; Cui, Bianxiao; PaÈca, Sergiu P; Cui, Yi; Habtezion, Aida; Chen, Xiaoke; Bao, Zhenan.

Nature ; 606(7912): 94-101, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35650358

8.

A nomenclature consensus for nervous system organoids and assembloids.

PaÈca, Sergiu P; Arlotta, Paola; Bateup, Helen S; Camp, J Gray; Cappello, Silvia; Gage, Fred H; Knoblich, Jürgen A; Kriegstein, Arnold R; Lancaster, Madeline A; Ming, Guo-Li; Muotri, Alysson R; Park, In-Hyun; Reiner, Orly; Song, Hongjun; Studer, Lorenz; Temple, Sally; Testa, Giuseppe; Treutlein, Barbara; Vaccarino, Flora M.

Nature ; 609(7929): 907-910, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36171373

9.

Primate cell fusion disentangles gene regulatory divergence in neurodevelopment.

Agoglia, Rachel M; Sun, Danqiong; Birey, Fikri; Yoon, Se-Jin; Miura, Yuki; Sabatini, Karen; PaÈca, Sergiu P; Fraser, Hunter B.

Nature ; 592(7854): 421-427, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33731928

10.

The rise of three-dimensional human brain cultures.

PaÈca, Sergiu P.

Nature ; 553(7689): 437-445, 2018 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-29364288

11.

Mouse embryo models built from stem cells take shape in a dish.

Amin, Neal D; PaÈca, Sergiu P.

Nature ; 610(7930): 39-40, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36192499

12.

Reliability of human cortical organoid generation.

Yoon, Se-Jin; Elahi, Lubayna S; PaÈca, Anca M; Marton, Rebecca M; Gordon, Aaron; Revah, Omer; Miura, Yuki; Walczak, Elisabeth M; Holdgate, Gwendolyn M; Fan, H Christina; Huguenard, John R; Geschwind, Daniel H; PaÈca, Sergiu P.

Nat Methods ; 16(1): 75-78, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30573846

13.

Absent forebrain replaced by embryonic stem cells.

Andersen, Jimena; PaÈca, Sergiu P.

Nature ; 563(7729): 44-45, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30375499

14.

The ethics of experimenting with human brain tissue.

Farahany, Nita A; Greely, Henry T; Hyman, Steven; Koch, Christof; Grady, Christine; PaÈca, Sergiu P; Sestan, Nenad; Arlotta, Paola; Bernat, James L; Ting, Jonathan; Lunshof, Jeantine E; Iyer, Eswar P R; Hyun, Insoo; Capestany, Beatrice H; Church, George M; Huang, Hao; Song, Hongjun.

Nature ; 556(7702): 429-432, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29691509

15.

Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids.

Yang, Xiao; Forró, Csaba; Li, Thomas L; Miura, Yuki; Zaluska, Tomasz J; Tsai, Ching-Ting; Kanton, Sabina; McQueen, James P; Chen, Xiaoyu; Mollo, Valentina; Santoro, Francesca; PaÈca, Sergiu P; Cui, Bianxiao.

Nat Biotechnol ; 2024 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-38253880

16.

A Cross-Sectional Study of the Neuropsychiatric Phenotype of CACNA1C-Related Disorder.

Levy, Rebecca J; Timothy, Katherine W; Underwood, Jack F G; Hall, Jeremy; Bernstein, Jonathan A; PaÈca, Sergiu P.

Pediatr Neurol ; 138: 101-106, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36436328

17.

Single-cell transcriptomic landscape of the developing human spinal cord.

Andersen, Jimena; Thom, Nicholas; Shadrach, Jennifer L; Chen, Xiaoyu; Onesto, Massimo Mario; Amin, Neal D; Yoon, Se-Jin; Li, Li; Greenleaf, William J; Müller, Fabian; PaÈca, Anca M; Kaltschmidt, Julia A; PaÈca, Sergiu P.

Nat Neurosci ; 26(5): 902-914, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37095394

18.

Spatially controlled construction of assembloids using bioprinting.

Roth, Julien G; Brunel, Lucia G; Huang, Michelle S; Liu, Yueming; Cai, Betty; Sinha, Sauradeep; Yang, Fan; PaÈca, Sergiu P; Shin, Sungchul; Heilshorn, Sarah C.

Nat Commun ; 14(1): 4346, 2023 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-37468483

19.

Chromatin dynamics in human brain development and disease.

Valencia, Alfredo M; PaÈca, Sergiu P.

Trends Cell Biol ; 32(2): 98-101, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34610892

20.

Imaging neuronal migration and network activity in human forebrain assembloids.

Birey, Fikri; PaÈca, Sergiu P.

STAR Protoc ; 3(3): 101478, 2022 09 16.

Artigo em Inglês | MEDLINE | ID: mdl-35769932

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