Detalhe da pesquisa
1.
SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation.
Proc Natl Acad Sci U S A
; 118(8)2021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597301
2.
Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice.
Dev Biol
; 477: 49-63, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34010606
3.
Periarticular Mesenchymal Progenitors Initiate and Contribute to Secondary Ossification Center Formation During Mouse Long Bone Development.
Stem Cells
; 37(5): 677-689, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30681752
4.
Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
PLoS Genet
; 13(4): e1006742, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445472
5.
Domains with highest heparan sulfate-binding affinity reside at opposite ends in BMP2/4 versus BMP5/6/7: Implications for function.
J Biol Chem
; 293(37): 14371-14383, 2018 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082319
6.
Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in hereditary multiple exostoses.
J Biol Chem
; 293(20): 7703-7716, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29622677
7.
Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs.
Dev Biol
; 426(1): 56-68, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438606
8.
Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference.
Connect Tissue Res
; 59(1): 85-98, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29099240
9.
Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.
Curr Osteoporos Rep
; 15(3): 142-152, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28466453
10.
HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling.
J Cell Physiol
; 231(5): 1033-44, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26363135
11.
Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: a mechanism possibly involved in hereditary multiple exostoses.
Am J Pathol
; 185(6): 1676-85, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25863260
12.
Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin.
Dev Biol
; 395(2): 255-67, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25238962
13.
Delayed hypertrophic differentiation of epiphyseal chondrocytes contributes to failed secondary ossification in mucopolysaccharidosis VII dogs.
Mol Genet Metab
; 116(3): 195-203, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26422116
14.
Interactions of signaling proteins, growth factors and other proteins with heparan sulfate: mechanisms and mysteries.
Connect Tissue Res
; 56(4): 272-80, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26076122
15.
Articular Cartilage: Structural and Developmental Intricacies and Questions.
Curr Osteoporos Rep
; 13(6): 407-14, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26408155
16.
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
Dev Biol
; 377(1): 100-12, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23458899
17.
Loss of ß-catenin induces multifocal periosteal chondroma-like masses in mice.
Am J Pathol
; 182(3): 917-27, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23274133
18.
Multiple hereditary exostoses (MHE): elucidating the pathogenesis of a rare skeletal disorder through interdisciplinary research.
Connect Tissue Res
; 55(2): 80-8, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24409815
19.
Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses.
Dev Dyn
; 242(9): 1021-32, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23821404
20.
Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.
Development
; 137(22): 3795-800, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20978074