Detalhe da pesquisa
1.
Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth.
Org Biomol Chem
; 22(17): 3425-3438, 2024 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38590227
2.
Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases.
Bioorg Chem
; 145: 107168, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38354500
3.
Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction.
J Enzyme Inhib Med Chem
; 39(1): 2302920, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38221785
4.
Microwave-induced one-pot synthesis of 3-imidazolyl indole clubbed 1,2,3-triazole hybrids as antiproliferative agents and density functional theory study.
Arch Pharm (Weinheim)
; 357(3): e2300632, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38150663
5.
Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity.
Bioorg Med Chem
; 92: 117417, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531922
6.
Biotinylated selenocyanates: Potent and selective cytostatic agents.
Bioorg Chem
; 133: 106410, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36822000
7.
An efficient one-pot synthesis and docking studies of bioactive new antiproliferative dispiro[oxindole/acenaphthylenoneâbenzofuranone] pyrrolidine scaffolds.
Mol Divers
; 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935912
8.
Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers.
J Enzyme Inhib Med Chem
; 38(1): 349-360, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458374
9.
Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors.
Int J Mol Sci
; 24(11)2023 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298353
10.
Iron(III)-Catalyzed Synthesis of 2-Alkyl Homoallyl Sulfonyl Amides: Antiproliferative Study and Reactivity Scope of Aza-Prins Cyclization.
J Org Chem
; 87(16): 11000-11006, 2022 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921221
11.
Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease.
Bioorg Chem
; 127: 105983, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35779403
12.
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE).
J Enzyme Inhib Med Chem
; 37(1): 2395-2402, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36065944
13.
2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases.
J Enzyme Inhib Med Chem
; 37(1): 168-177, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894971
14.
Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations.
Int J Mol Sci
; 23(14)2022 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35887037
15.
Early Pharmacological Profiling of Antiproliferative Compounds by Live Cell Imaging.
Molecules
; 27(16)2022 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36014500
16.
Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids-A Biological Assessment.
Molecules
; 27(4)2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209105
17.
Oxonitrogenated Derivatives of Eremophilans and Eudesmans: Antiproliferative and Anti-Trypanosoma cruzi Activity.
Molecules
; 27(10)2022 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35630539
18.
Bioactive Potential: A Pharmacognostic Definition through the Screening of Four Hypericum Species from the Canary Islands.
Molecules
; 27(18)2022 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36144833
19.
Repurposing old drugs to fight multidrug resistant cancers.
Drug Resist Updat
; 52: 100713, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32615525
20.
Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors.
J Enzyme Inhib Med Chem
; 36(1): 138-146, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228403