Detalhe da pesquisa
1.
Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain.
Blood
; 141(10): 1221-1232, 2023 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580664
2.
Conformation of the von Willebrand factor/factor VIII complex in quasi-static flow.
J Biol Chem
; 296: 100420, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33600794
3.
Frequency and epitope specificity of anti-factor VIII C1 domain antibodies in acquired and congenital hemophilia A.
Blood
; 130(6): 808-816, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28507083
4.
A subset of high-titer anti-factor VIII A2 domain antibodies is responsive to treatment with factor VIII.
Blood
; 127(16): 2028-34, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825708
5.
High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors.
Blood
; 128(16): 2055-2067, 2016 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381905
6.
The diversity of the immune response to the A2 domain of human factor VIII.
Blood
; 121(14): 2785-95, 2013 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23349389
7.
A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.
Blood
; 120(12): 2512-20, 2012 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22855607
8.
Nanobody activator improves sensitivity of the von Willebrand factor activity assay to multimer size.
J Thromb Haemost
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704122
9.
Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein.
Blood
; 117(11): 3190-8, 2011 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21217077
10.
Lentiviral vector platform for production of bioengineered recombinant coagulation factor VIII.
Mol Ther
; 19(2): 302-9, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081907
11.
Subunit Flexibility of Multimeric von Willebrand Factor/Factor VIII Complexes.
ACS Omega
; 7(35): 31183-31196, 2022 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36092565
12.
Removal of single-site N-linked glycans on factor VIII alters binding of domain-specific monoclonal antibodies.
J Thromb Haemost
; 20(3): 574-588, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34863021
13.
Neutralizing Antibodies Against Factor VIII Can Occur Through a Non-Germinal Center Pathway.
Front Immunol
; 13: 880829, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35634288
14.
Engineering a Therapeutic Protein to Enhance the Study of Anti-Drug Immunity.
Biomedicines
; 10(7)2022 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35885029
15.
Measurement of the Translational Diffusion Coefficient and Hydrodynamic Radius of Proteins by Dynamic Light Scattering.
Bio Protoc
; 11(20): e4195, 2021 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34761067
16.
Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction.
Blood Adv
; 5(17): 3333-3343, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34477814
17.
Nonclassical anti-C2 domain antibodies are present in patients with factor VIII inhibitors.
Blood
; 112(4): 1151-3, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18495957
18.
The 3.2 Å structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain.
J Thromb Haemost
; 18(1): 57-69, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454152
19.
The comparative immunogenicity of human and porcine factor VIII in haemophilia A mice.
Thromb Haemost
; 102(1): 35-41, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19572065
20.
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa.
J Drug Target
; 16(3): 185-97, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18365880