Extensive deep vein thrombosis in a young girl with absent inferior vena cava and iliac veins: a case report.

Congenital absence of inferior vena cava (IVC) and iliac veins is a rare anomaly that can predispose young patients to develop deep vein thrombosis (DVT). This case report highlights the importance of considering this anatomical abnormality in young patients with unprovoked DVT. We present the case of a 17-year-old girl who visited the emergency department (ED) complaining of right leg pain and swelling for 8 days. An ED ultrasound revealed extensive DVT in the right leg veins, and further investigation with abdominal computed tomography revealed that the patient's IVC and iliac veins were absent and showed the presence of thrombosis. The patient underwent thrombectomy and angioplasty by interventional radiology and was given a lifetime prescription for oral anticoagulation. When treating young, otherwise healthy individuals with unprovoked DVT, Clinicians should include absent IVC in their differential when treating young, otherwise healthy patients with unprovoked DVT.

Theoretical Study of Non-Isothermal Gradient Elution Liquid Chromatography.

A two-component model of gradient elution chromatography is investigated to theoretically study the effects of simultaneous variations in temperature and solvent strength on the retention behaviors of elution profiles in thermally insulated liquid chromatographic columns. The gradient elution technique is based on the gradual increase or decrease in eluent strength during the chromatographic operation by varying the composition of the mobile phase. The enthalpy of adsorption is primarily responsible for internal temperature variations inside the column, as heat adsorbs during the adsorption process and releases in the desorption phase. Both types of variations change the propagation speeds of moving pulses inside the column which can lead to better separation of the components and a reduction in the recycling time for the next injection. The equilibrium dispersive model (EDM) coupled with the energy balance equation for temperature and transport equation for the volume fraction of the solvent is utilized to simulate this complex process. The resulting nonlinear model equations are approximated by applying a semi-discrete second-order finite volume scheme. The numerical solutions are used to study the impact of a gradient starting and ending times, volume-fraction of the solvent, solvent strength parameter, the slope of gradient, enthalpy of adsorption, injection temperature, and the ratio of specific heats on the concentration profiles.

Prevalence of work-related musculoskeletal disorders among health care professionals: A systematic review.

BACKGROUND: Work-related musculoskeletal disorders (WRMSDs) are one of the main causes of morbidity among healthcare professionals. It has various secondary consequences on productivity by diminishing the quantity and quality of work completed by the affected personnel, in addition to having a primary impact on the individual with pain and discomfort. OBJECTIVE: The study aims to determine the overall prevalence rate of WRMSD among dentists, physiotherapists, and surgeons and also identify the commonly affected regions of the body about specific health care professions among each of the three professions, as recorded by the cross-sectional studies performed in various countries and regions of the world. METHODS: A systematic search strategy was framed following the PRISMA guidelines based on the present inclusion and exclusion criteria. A critical search of articles was conducted during June 2020 in CINAHL (DOAJ), PubMed, Google Scholar Scopus, PEDro databases and SAGE journals. RESULTS: Out of the 42 articles that met the eligibility criteria, there were 39 cross-sectional studies, 2 pilot cross-sectional surveys and 1 prospective cohort study with one-year follow-up. All studies included in this review used various survey tools for recording the demographic details and measuring the prevalence of WRMSDs and other outcome factors. CONCLUSION: We conclude that all three health care professionals (dentists, physiotherapists and surgeons) are highly prone to develop WRMSDs with surgeons and dentists being more vulnerable when compared to physiotherapists. The lower back and neck are identified as the two most commonly affected regions among all three professionals.

Study of antimicrobial activity of Unani poly herbal toothpaste "Sunoon Zard".

OBJECTIVE: The present study was envisioned to develop Sunoon Zard a traditional Unani toothpowder into toothpaste form along with its physicochemical standardization and evaluation of anti microbial activity against oral pathogens by in vitro study. MATERIALS AND METHODS: Herbal extracts based powder was redesigned to toothpaste as per the Pharmacopoeial guidelines and its pharmaceutical evaluation was conceded as per the Indian Government Tooth Paste Specifications. In vitro study was done to evaluate the antibacterial activity by using agar well diffusion method against dental pathogens. Zone of Inhibition was taken as the end parameter against the test pathogens after appropriate incubation period. It was compared with Dimethyl sulphoxide (DMSO) used as solvent (0.01%) as Negative control whereas Ciprofloxacin 5µg/disk (standard antibiotic for gram positive) and Gentamicin 10µg/disk (standard antibiotic for gram negative) were used as Positive control. All the experiment was done as per the Clinical and Laboratory Standards Institute (CLSI) Guidelines in triplicates. RESULTS: Sunoon Zard was developed into toothpaste form and its physicochemical values were found to in consonance with the optimum values as mentioned in Bureau of Indian Standard. In vitro study of the Sunoon Zard toothpaste was found to be effective against various dental pathogens with specific sensitivity with good zone of inhibition towards gram negative bacterial strains viz. P.aeruginosa and K.pneuomoniae while among gram positive a significant inhibition was found against C.xerosis and S.viridans. CONCLUSION: The developed toothpaste from classical Unani herbal tooth powder will provide the better patient compliance. Moreover its scientific screening which exhibited potential antibacterial activity in controlling pathogenic oral microflora compared to the standard drugs also revalidated the claim of Unani Physicians that the Sunoon Zard is quite effective in various oro-dental disorders.

Root and Root Canal Morphology Classification Systems.

INTRODUCTION: While there are many root morphology classification systems with their own distinct advantages, there are many shortcomings that come along with each system. OBJECTIVES: The aim of this review was to compare the various root and root canal morphology classifications, their advantages, limitations, and clinical and research implications. Data Sources and Selection. An extensive literature search was conducted on PubMed and Scopus to identify the published data on root and root canal classification systems published until 1 May 2020 using keywords, root canal classification system, classification systems for root canals, and root morphology. The related literature was reviewed and then summarized. Data Synthesis. Several studies have analysed and detailed root and root canal classifications and further added new subsystems, works of Weine et al. (1969) and Vertucci et al. (1974). Besides, Sert and Bayirli (2004) added supplementary types to Vertucci's classification system. A new classification was most recently introduced by Ahmed et al. (2017) involving the use of codes for tooth numbering, number of roots, and canal configuration. CONCLUSIONS: Weine et al. classified only single-rooted teeth, without considering multirooted teeth and complex configurations. Vertucci's classification included complex configurations, with Sert and Bayirli adding further complex supplemental types. Ahmed et al.'s classification simplifies classifying root and canal morphology while overcoming the limitations of several previous classification systems making it beneficial for implementation in dental schools.