Detalhe da pesquisa
1.
Discovery and characterization of novel Cre-type tyrosine site-specific recombinases for advanced genome engineering.
Nucleic Acids Res
; 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37158248
2.
Precise excision of HTLV-1 provirus with a designer-recombinase.
Mol Ther
; 31(7): 2266-2285, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36934299
3.
MLLT6 maintains PD-L1 expression and mediates tumor immune resistance.
EMBO Rep
; 21(12): e50155, 2020 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33063451
4.
A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus.
Nucleic Acids Res
; 48(1): 472-485, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31745551
5.
CRISPR/Cas9 as a tool to dissect cancer mutations.
Methods
; 164-165: 36-48, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31078796
6.
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.
EMBO Rep
; 18(6): 929-946, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500257
7.
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug.
Blood
; 125(24): 3760-8, 2015 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25931586
8.
Combined RNAi and localization for functionally dissecting long noncoding RNAs.
Nat Methods
; 9(4): 360-2, 2012 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22327834
9.
Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells.
Blood
; 119(18): 4152-61, 2012 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22411870
10.
Multipose binding in molecular docking.
Int J Mol Sci
; 15(2): 2622-45, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24534807
11.
Nucleolar protein TAAP1/C22orf46 confers pro-survival signaling in non-small cell lung cancer.
Life Sci Alliance
; 7(4)2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228372
12.
Activation of recombinases at specific DNA loci by zinc-finger domain insertions.
Nat Biotechnol
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297187
13.
Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1.
PLoS One
; 19(3): e0298542, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38457474
14.
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.
EMBO J
; 28(10): 1453-65, 2009 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19387489
15.
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.
PLoS Biol
; 8(6): e1000408, 2010 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20613862
16.
CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability.
Small Methods
; 7(6): e2201605, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36908010
17.
Prediction of designer-recombinases for DNA editing with generative deep learning.
Nat Commun
; 13(1): 7966, 2022 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36575171
18.
RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations.
Cells
; 11(5)2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35269477
19.
Correction of a Factor VIII genomic inversion with designer-recombinases.
Nat Commun
; 13(1): 422, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058465
20.
The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells.
Life Sci Alliance
; 4(3)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33376128