Pesquisa | BVS Violência e Saúde

1.

PIEZO2 in somatosensory neurons controls gastrointestinal transit.

Servin-Vences, M Rocio; Lam, Ruby M; Koolen, Alize; Wang, Yu; Saade, Dimah N; Loud, Meaghan; Kacmaz, Halil; Frausto, Suzanne; Zhang, Yunxiao; Beyder, Arthur; Marshall, Kara L; Bönnemann, Carsten G; Chesler, Alexander T; Patapoutian, Ardem.

Cell ; 186(16): 3386-3399.e15, 2023 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-37541196

2.

A role of PIEZO1 in iron metabolism in mice and humans.

Ma, Shang; Dubin, Adrienne E; Zhang, Yunxiao; Mousavi, Seyed Ali Reza; Wang, Yu; Coombs, Adam M; Loud, Meaghan; Andolfo, Immacolata; Patapoutian, Ardem.

Cell ; 184(4): 969-982.e13, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33571427

3.

GPR68 Senses Flow and Is Essential for Vascular Physiology.

Xu, Jie; Mathur, Jayanti; Vessières, Emilie; Hammack, Scott; Nonomura, Keiko; Favre, Julie; Grimaud, Linda; Petrus, Matt; Francisco, Allain; Li, Jingyuan; Lee, Van; Xiang, Fu-Li; Mainquist, James K; Cahalan, Stuart M; Orth, Anthony P; Walker, John R; Ma, Shang; Lukacs, Viktor; Bordone, Laura; Bandell, Michael; Laffitte, Bryan; Xu, Yan; Chien, Shu; Henrion, Daniel; Patapoutian, Ardem.

Cell ; 173(3): 762-775.e16, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29677517

4.

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.

Ma, Shang; Cahalan, Stuart; LaMonte, Gregory; Grubaugh, Nathan D; Zeng, Weizheng; Murthy, Swetha E; Paytas, Emma; Gamini, Ramya; Lukacs, Viktor; Whitwam, Tess; Loud, Meaghan; Lohia, Rakhee; Berry, Laurence; Khan, Shahid M; Janse, Chris J; Bandell, Michael; Schmedt, Christian; Wengelnik, Kai; Su, Andrew I; Honore, Eric; Winzeler, Elizabeth A; Andersen, Kristian G; Patapoutian, Ardem.

Cell ; 173(2): 443-455.e12, 2018 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-29576450

5.

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.

Syeda, Ruhma; Qiu, Zhaozhu; Dubin, Adrienne E; Murthy, Swetha E; Florendo, Maria N; Mason, Daniel E; Mathur, Jayanti; Cahalan, Stuart M; Peters, Eric C; Montal, Mauricio; Patapoutian, Ardem.

Cell ; 164(3): 499-511, 2016 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-26824658

6.

Piezos thrive under pressure: mechanically activated ion channels in health and disease.

Murthy, Swetha E; Dubin, Adrienne E; Patapoutian, Ardem.

Nat Rev Mol Cell Biol ; 18(12): 771-783, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28974772

7.

SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.

Qiu, Zhaozhu; Dubin, Adrienne E; Mathur, Jayanti; Tu, Buu; Reddy, Kritika; Miraglia, Loren J; Reinhardt, Jürgen; Orth, Anthony P; Patapoutian, Ardem.

Cell ; 157(2): 447-458, 2014 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-24725410

8.

Direct observation of the conformational states of PIEZO1.

Mulhall, Eric M; Gharpure, Anant; Lee, Rachel M; Dubin, Adrienne E; Aaron, Jesse S; Marshall, Kara L; Spencer, Kathryn R; Reiche, Michael A; Henderson, Scott C; Chew, Teng-Leong; Patapoutian, Ardem.

Nature ; 620(7976): 1117-1125, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37587339

9.

PIEZO1 transduces mechanical itch in mice.

Hill, Rose Z; Loud, Meaghan C; Dubin, Adrienne E; Peet, Brooke; Patapoutian, Ardem.

Nature ; 607(7917): 104-110, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35732741

10.

The role of somatosensory innervation of adipose tissues.

Wang, Yu; Leung, Verina H; Zhang, Yunxiao; Nudell, Victoria S; Loud, Meaghan; Servin-Vences, M Rocio; Yang, Dong; Wang, Kristina; Moya-Garzon, Maria Dolores; Li, Veronica L; Long, Jonathan Z; Patapoutian, Ardem; Ye, Li.

Nature ; 609(7927): 569-574, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36045288

11.

Why does morphine make you itch?

Miyamoto, Takashi; Patapoutian, Ardem.

Cell ; 147(2): 261-2, 2011 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-22000005

12.

PIEZO2 in sensory neurons and urothelial cells coordinates urination.

Marshall, Kara L; Saade, Dimah; Ghitani, Nima; Coombs, Adam M; Szczot, Marcin; Keller, Jason; Ogata, Tracy; Daou, Ihab; Stowers, Lisa T; Bönnemann, Carsten G; Chesler, Alexander T; Patapoutian, Ardem.

Nature ; 588(7837): 290-295, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33057202

13.

Itching for insight.

Bandell, Michael; Patapoutian, Ardem.

Cell ; 139(7): 1224-6, 2009 Dec 24.

Artigo em Inglês | MEDLINE | ID: mdl-20064368

14.

Structure of the mechanically activated ion channel Piezo1.

Saotome, Kei; Murthy, Swetha E; Kefauver, Jennifer M; Whitwam, Tess; Patapoutian, Ardem; Ward, Andrew B.

Nature ; 554(7693): 481-486, 2018 02 22.

Artigo em Inglês | MEDLINE | ID: mdl-29261642

15.

PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana.

Mousavi, Seyed A R; Dubin, Adrienne E; Zeng, Wei-Zheng; Coombs, Adam M; Do, Khai; Ghadiri, Darian A; Keenan, William T; Ge, Chennan; Zhao, Yunde; Patapoutian, Ardem.

Proc Natl Acad Sci U S A ; 118(20)2021 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-33975957

16.

Author Correction: Structure of the mechanically activated ion channel Piezo1.

Saotome, Kei; Murthy, Swetha E; Kefauver, Jennifer M; Whitwam, Tess; Patapoutian, Ardem; Ward, Andrew B.

Nature ; 607(7919): E10, 2022 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-35788193

17.

Piezo2 senses airway stretch and mediates lung inflation-induced apnoea.

Nonomura, Keiko; Woo, Seung-Hyun; Chang, Rui B; Gillich, Astrid; Qiu, Zhaozhu; Francisco, Allain G; Ranade, Sanjeev S; Liberles, Stephen D; Patapoutian, Ardem.

Nature ; 541(7636): 176-181, 2017 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-28002412

18.

Heterozygous Variants in the Mechanosensitive Ion Channel TMEM63A Result in Transient Hypomyelination during Infancy.

Yan, Huifang; Helman, Guy; Murthy, Swetha E; Ji, Haoran; Crawford, Joanna; Kubisiak, Thomas; Bent, Stephen J; Xiao, Jiangxi; Taft, Ryan J; Coombs, Adam; Wu, Ye; Pop, Ana; Li, Dongxiao; de Vries, Linda S; Jiang, Yuwu; Salomons, Gajja S; van der Knaap, Marjo S; Patapoutian, Ardem; Simons, Cas; Burmeister, Margit; Wang, Jingmin; Wolf, Nicole I.

Am J Hum Genet ; 105(5): 996-1004, 2019 11 07.

Artigo em Inglês | MEDLINE | ID: mdl-31587869

19.

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.

Nonomura, Keiko; Lukacs, Viktor; Sweet, Daniel T; Goddard, Lauren M; Kanie, Akemi; Whitwam, Tess; Ranade, Sanjeev S; Fujimori, Toshihiko; Kahn, Mark L; Patapoutian, Ardem.

Proc Natl Acad Sci U S A ; 115(50): 12817-12822, 2018 12 11.

Artigo em Inglês | MEDLINE | ID: mdl-30482854

20.

Piezo2 is required for Merkel-cell mechanotransduction.

Woo, Seung-Hyun; Ranade, Sanjeev; Weyer, Andy D; Dubin, Adrienne E; Baba, Yoshichika; Qiu, Zhaozhu; Petrus, Matt; Miyamoto, Takashi; Reddy, Kritika; Lumpkin, Ellen A; Stucky, Cheryl L; Patapoutian, Ardem.

Nature ; 509(7502): 622-6, 2014 May 29.

Artigo em Inglês | MEDLINE | ID: mdl-24717433

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