Diagnostic accuracy of computed tomography in adults with suspected acute appendicitis at the emergency department in a private tertiary hospital in Tanzania.

INTRODUCTION: The increasing incidence of acute appendicitis in sub-Saharan Africa emphasizes the need for accurate and reliable diagnostic tools. However, the variability in the diagnostic performance of computed tomography for suspected acute appendicitis coupled with comparatively higher negative appendectomy rates in this setting highlight a possible concern regarding the diagnostic accuracy. This study evaluated the diagnostic accuracy of a computed tomography scan for suspected acute appendicitis at the emergency department in Tanzania. METHODS: A retrospective diagnostic accuracy study was conducted from July to October 2020. All patients above 14 years of age who presented at the emergency department with right iliac fossa abdominal pain of fewer than ten days and underwent computed tomography for suspected acute appendicitis were evaluated, and the Alvarado score was computed. Histological diagnosis and clinical follow-up of 14 days were considered the reference standard. Ethical clearance was sought from the Aga Khan University Ethical review committee. RESULTS: 176 patients were included in this study. The sensitivity, specificity, and diagnostic accuracy were 100% (95% CI 91.8-100), 96.9% (95% CI 92.2-99.1), and 96.9% (95% CI 93.1-98.3), respectively. The mean Alvarado score in those without acute appendicitis was 4 (95% CI 3.7-4.3) compared to a mean score of 6.6 (95% CI 6.0-7.2) amongst those with acute appendicitis. The area under the receiver operator characteristics curve of computed tomography was 98.4%, and that of the Alvarado score was 84.1%. CONCLUSIONS: The diagnostic performance of computed tomography in this study is similar to that established elsewhere. However, the Alvarado score is not routinely used for the initial screening of suspected acute appendicitis patients. A threshold of Alvarado score of 4 as a guide to conduct computed tomography for suspected acute appendicitis would have decreased computed tomography use by 50%, and missed 4 cases. Implementation studies that address Alvarado score use should be conducted.

A missing piece: Fracture of peripheral intravenous cannula, a case report.

INTRODUCTION AND IMPORTANCE: Peripheral venous cannulation is the most common procedure, often performed by junior colleagues. Despite its benign nature, it is associated with extravascular infiltration, thrombophlebitis, hematoma, catheter-associated bloodstream infections, trauma to surrounding structures, including tendon and nerve injures, hematoma formation and air embolism. Fracture of a peripheral intravenous cannula in situ is a rare, potentially serious complication that is underreported. More importantly, the etiology and prevention of this complication are not widely known by those performing cannulation. This case report will increase awareness and knowledge on intravenous peripheral cannula fracture to improve peripheral intravenous cannulation safety. CASE PRESENTATION: In this case report, we describe a fracture of a size 18 G plastic peripheral intravenous cannula (Neovac-Neomedic) in situ in a 76-year-old hypertensive male managed at Aga Khan Hospital Dar es salaam, Tanzania. The cannula's fracture was noticed 24 h later during the cannula's removal, where a fragment of the cannula was noted, and a palpable cord-like structure was appreciated along the cubital fossa. Ultrasound was done to localize the distal segment, confirming a cannula fracture with the distal fragment's retention. Surgical exploration under local anesthetic was necessary, retrieving the fragment. There were no intra-operatively or post-operative complications encountered. Proximal migration of the segment risks the chances of developing sepsis, dysrhythmia, and myocardial infarction, but this did not occur in our case. CLINICAL DISCUSSION: Reinsertion of the guide needle into the plastic sheath in situ most probably caused the fracture. Additional healthcare costs are incurred for investigation, admission, and surgical procedures. The patient experience may be affected by this complication. CONCLUSION: Understanding the guide needle's reinsertion may result in cannula fracture, allows safer cannulation practices by the clinician and adequate counseling of the patient before the procedure.