Detalhe da pesquisa
1.
Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: identification of a selective inhibitor of hormone-independent breast cancer cells.
Bioorg Med Chem
; 23(4): 703-11, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25619894
2.
Synthesis, structural analysis and antitumor activity of novel 17α-picolyl and 17(E)-picolinylidene A-modified androstane derivatives.
Bioorg Med Chem
; 23(7): 1557-68, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737400
3.
Androstane derivatives induce apoptotic death in MDA-MB-231 breast cancer cells.
Bioorg Med Chem
; 23(22): 7189-98, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494582
4.
Determination of 17α-hydroxylase-C17,20-lyase (P45017α) enzyme activities and their inhibition by selected steroidal picolyl and picolinylidene compounds.
Acta Biol Hung
; 66(1): 41-51, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25740437
5.
The effect of the androstane lung cancer inhibitor content on the cell-selective toxicity of hydroxyapatite-chitosan-PLGA nanocomposites.
Mater Sci Eng C Mater Biol Appl
; 89: 371-377, 2018 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29752109
6.
Lipophilicity estimation and characterization of selected steroid derivatives of biomedical importance applying RP HPLC.
J Pharm Biomed Anal
; 134: 27-35, 2017 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27871054
7.
Chemometrics approach based on chromatographic behavior, in silico characterization and molecular docking study of steroid analogs with biomedical importance.
Eur J Pharm Sci
; 105: 71-81, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28479347
8.
Selective anticancer activity of hydroxyapatite/chitosan-poly(d,l)-lactide-co-glycolide particles loaded with an androstane-based cancer inhibitor.
Colloids Surf B Biointerfaces
; 148: 629-639, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694053
9.
HPTLC chromatography of androstene derivates. Application of normal phase thin-layer chromatographic retention data in QSAR studies.
Steroids
; 70(3): 137-44, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15763591
10.
Microwave assisted synthesis and biomedical potency of salicyloyloxy and 2-methoxybenzoyloxy androstane and stigmastane derivatives.
Steroids
; 94: 31-40, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25541058
11.
Synthesis, X-ray crystal structures and biological activity of 16-amino-17-substituted-D-homo steroid derivatives.
Steroids
; 68(7-8): 667-76, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12957672
12.
Synthesis and cytotoxic activity of some 17-picolyl and 17-picolinylidene androstane derivatives.
Eur J Med Chem
; 54: 784-92, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22770744
13.
Synthesis and antitumor activity of new D-seco and D-homo androstane derivatives.
Steroids
; 74(12): 983-8, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19646459