Detalhe da pesquisa
1.
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature
; 625(7993): 195-203, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123684
2.
The SDS22:PP1:I3 complex: SDS22 binding to PP1 loosens the active site metal to prime metal exchange.
J Biol Chem
; 300(1): 105515, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38042495
3.
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling.
J Biol Chem
; : 107393, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777143
4.
Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol Cell
; 65(4): 644-658.e5, 2017 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28212750
5.
MqsR is a noncanonical microbial RNase toxin that is inhibited by antitoxin MqsA via steric blockage of substrate binding.
J Biol Chem
; 298(11): 102535, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162504
6.
Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation.
J Biol Chem
; 298(2): 101557, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34974059
7.
Penicillin-Binding Proteins and Alternative Dual-Beta-Lactam Combinations for Serious Enterococcus faecalis Infections with Elevated Penicillin MICs.
Antimicrob Agents Chemother
; 67(2): e0087122, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719223
8.
EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics.
EMBO Rep
; 22(4): e50835, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33586867
9.
SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc Natl Acad Sci U S A
; 116(41): 20472-20481, 2019 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548429
10.
Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity.
Biochemistry
; 60(51): 3856-3867, 2021 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910875
11.
Cooperative dynamics across distinct structural elements regulate PTP1B activity.
J Biol Chem
; 295(40): 13829-13837, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737198
12.
NMR Based SARS-CoV-2 Antibody Screening.
J Am Chem Soc
; 143(21): 7930-7934, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34018723
13.
Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors.
Bioorg Med Chem
; 48: 116418, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34563877
14.
Dynamic activation and regulation of the mitogen-activated protein kinase p38.
Proc Natl Acad Sci U S A
; 115(18): 4655-4660, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666261
15.
A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans.
Mol Cell Proteomics
; 17(12): 2448-2461, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228194
16.
A peculiar IclR family transcription factor regulates para-hydroxybenzoate catabolism in Streptomyces coelicolor.
Nucleic Acids Res
; 46(3): 1501-1512, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29240934
17.
Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization.
Biochemistry
; 58(41): 4183-4194, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566355
18.
A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.
J Biol Chem
; 293(20): 7766-7776, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29618508
19.
The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into ß-lactam resistance.
J Biol Chem
; 293(48): 18574-18584, 2018 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355734
20.
The KIM-family protein-tyrosine phosphatases use distinct reversible oxidation intermediates: Intramolecular or intermolecular disulfide bond formation.
J Biol Chem
; 292(21): 8786-8796, 2017 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28389559