Detalhe da pesquisa
1.
Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load.
PLoS Comput Biol
; 19(8): e1011425, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37616311
2.
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding.
EMBO Rep
; 23(11): e51709, 2022 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36094794
3.
Mechanisms of phosphatidylserine influence on viral production: A computational model of Ebola virus matrix protein assembly.
J Biol Chem
; 298(7): 102025, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568195
4.
The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection.
J Theor Biol
; 534: 110949, 2022 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34717938
5.
Mathematical modeling of N-803 treatment in SIV-infected non-human primates.
PLoS Comput Biol
; 17(7): e1009204, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319980
6.
In Vitro Granuloma Models of Tuberculosis: Potential and Challenges.
J Infect Dis
; 219(12): 1858-1866, 2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30929010
7.
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30803965
8.
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.
PLoS Comput Biol
; 13(8): e1005650, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817561
9.
Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.
Infect Immun
; 84(5): 1650-1669, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26975995
10.
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment.
J Theor Biol
; 367: 166-179, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25497475
11.
A mathematical model of the initial interaction between Mycobacterium tuberculosis and macrophages.
J Theor Biol
; 342: 23-32, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24112967
12.
Evaluation of fendiline treatment in VP40 system with nucleation-elongation process: a computational model of Ebola virus matrix protein assembly.
Microbiol Spectr
; 12(4): e0309823, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38407984
13.
In silico agent-based modeling approach to characterize multiple in vitro tuberculosis infection models.
PLoS One
; 19(3): e0299107, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38517920
14.
Microglial roles in Alzheimer's disease: An agent-based model to elucidate microglial spatiotemporal response to beta-amyloid.
CPT Pharmacometrics Syst Pharmacol
; 13(3): 449-463, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38078626
15.
Reduced macrophage killing of M. avium drives infection risk in post-menopausal patients.
Tuberculosis (Edinb)
; 139: 102304, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682272
16.
Agent-based model indicates chemoattractant signaling caused by Mycobacterium avium biofilms in the lung airway increases bacterial loads by spatially diverting macrophages.
Tuberculosis (Edinb)
; 138: 102300, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36621288
17.
Evaluation of Fendiline Treatment in VP40 System with Nucleation-Elongation Process: A Computational Model of Ebola Virus Matrix Protein Assembly.
bioRxiv
; 2023 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577722
18.
"I Think I Am Getting There" Understanding the Computational Identity of Engineering Students Participating in a Computationally Intensive Thermodynamics Course.
Biomed Eng Educ
; 3(1): 1-21, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36090953
19.
Systems biology approaches to investigate the role of granulomas in TB-HIV coinfection.
Front Immunol
; 13: 1014515, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36405707
20.
Experimental Validation of a Fundamental Model for PCR Efficiency.
Chem Eng Sci
; 66(8): 1783-1789, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822325